| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1832 |
Name | DSP |
Synonymous | DCWHKTA|DP|DPI|DPII;desmoplakin;DSP;desmoplakin |
Definition | 250/210 kDa paraneoplastic pemphigus antigen|desmoplakin I|desmoplakin II |
Position | 6p24 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
desmoplakin(h) + plakoglobin(h){pY643} <==> desmoplakin(h):plakoglobin(h){pY643} (binding) | desmoplakin(h) + plakoglobin(h) <==> desmoplakin(h):plakoglobin(h) (binding) | GBDR1(h) + desmoplakin(h) <==> GBDR1(h):desmoplakin(h) (binding) | MST-3(h) + desmoplakin(h) <==> MST-3(h):desmoplakin(h) (binding) | DSP(h) --> desmoplakin(h) (expression). | DSP(h) --> desmoplakin-I(h) (expression). | DSP(h) --> desmoplakin-II(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
22 | Phosphoserine. | Swiss-Prot 53.0 | 176 | Phosphoserine. | Swiss-Prot 53.0 | 2024 | Phosphoserine. | Swiss-Prot 53.0 | 2209 | Phosphoserine. | Swiss-Prot 53.0 | 2480 | Omega-hydroxyceramide glutamate ester(Potential). | Swiss-Prot 53.0 | 2815 | Phosphoserine. | Swiss-Prot 53.0 | 2820 | Phosphoserine. | Swiss-Prot 53.0 | 2825 | Phosphoserine. | Swiss-Prot 53.0 | 2849 | Phosphoserine (by PKA) (Potential). | Swiss-Prot 53.0 | 2024 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 2825 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 2815 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 176 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 2209 | Phosphoserine | 15302935 | Phospho.ELM 6.0 | 22 | Phosphoserine | 16565220 | Phospho.ELM 6.0 | 2820 | Phosphoserine | 16565220 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr6 |
Promoter: 7485369 - 7487369 | Agilent_014791 |
chr6 |
Promoter: 7485369 - 7487369 | GoldenGate_Methylation_Cancer_Panel_I |
chr6 |
Promoter: 7485369 - 7487369 | GoldenGate_Methylation_Cancer_Panel_I |
chr6 |
Promoter: 7485369 - 7487369 | GSE27584 |
chr6 |
Promoter: 7485369 - 7487369 | GSE27584 |
chr6 |
Promoter: 7485369 - 7487369 | Agilent_014791_44K |