Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

1847

Name

DUSP5

Synonymous

DUSP|HVH3;dual specificity phosphatase 5;DUSP5;dual specificity phosphatase 5

Definition

VH1-like phosphatase 3|dual specificity protein phosphatase 5|dual specificity protein phosphatase hVH3|serine/threonine specific protein phosphatase

Position

10q25

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

DUSP5(h) --> DUSP5(h) (expression).
IL-2(m.s.) --> DUSP5(h) (increase of abundance)
ERK1(h){p} --DUSP5(h)--> ERK1(h) + p (dephosphorylation)
DUSP5(h) --> ERK2(m){pT183}{pY185} (decrease of phosphorylation)
DUSP5(h) --> ERK1(m){pT203}{pY205} (decrease of phosphorylation)
ERK1(m.s.) + DUSP5(h) <==> ERK1(m.s.):DUSP5(h) (binding)
DUSP5(h) + ERK2(m.s.) <==> DUSP5(h):ERK2(m.s.) (binding)
DUSP5(h) + JNK1(m.s.) <==> DUSP5(h):JNK1(m.s.) (binding)
ERK1(mo) + DUSP5(h) <==> ERK1(mo):DUSP5(h) (binding)
ERK2(mo) + DUSP5(h) <==> ERK2(mo):DUSP5(h) (binding)
DUSP5(h) --> DUSP5(h) (expression).
ERK2(m.s.){p} --DUSP5(h)--> ERK2(m.s.) + p (dephosphorylation)

Post Transcriptional Modification   [Top]

There is no record for DUSP5

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 112246115 - 112248115Agilent_014791

chr10

Promoter: 112246115 - 112248115GSE27584

chr10

Promoter: 112246115 - 112248115Agilent_014791_44K


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