Entrez Gene

Basic Information
Gene ID	1848
Name	DUSP6
Synonymous	HH19\|MKP3\|PYST1;dual specificity phosphatase 6;DUSP6;dual specificity phosphatase 6
Definition	MAP kinase phosphatase 3\|dual specificity protein phosphatase 6\|dual specificity protein phosphatase PYST1\|mitogen-activated protein kinase phosphatase 3\|serine/threonine specific protein phosphatase
Position	12q22-q23
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
MKP3(h) + ERK2(mo) <==> MKP3(h):ERK2(mo) (binding)
MKP3(h) + ERK2(m) <==> MKP3(h):ERK2(m) (binding)
MKP3(h) + I-MF(h) <==> MKP3(h):I-MF(h) (binding)
MKP3(h) + TGC1(h) <==> MKP3(h):TGC1(h) (binding)
DUSP6(h) --> MKP3(h) (expression).
ERK2(v.s.){p} --MKP3(h)--> ERK2(v.s.) + p (dephosphorylation)
DUSP6(h) --> MKP3-isoform1(h) (expression).
DUSP6(h) --> MKP3-isoform2(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
159	Phosphoserine (MAPK1;MAPK3)	15632084	Phospho.ELM 6.0