| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 2050 |
Name | EPHB4 |
Synonymous | HTK|MYK1|TYRO11;EPH receptor B4;EPHB4;EPH receptor B4 |
Definition | ephrin receptor EphB4|ephrin type-B receptor 4|hepatoma transmembrane kinase|soluble EPHB4 variant 1|soluble EPHB4 variant 2|soluble EPHB4 variant 3|tyrosine-protein kinase TYRO11|tyrosine-protein kinase receptor HTK |
Position | 7q22 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
 |
Transcription Factors [Top] |
|
Regulation From TransFac database |
c-Kit(h){pY} + EphB4(h) <==> c-Kit(h){pY}:EphB4(h) (binding) | EPHB4(h) --> EphB4(h) (expression). | EPHB4(h) --> EphB4(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
203 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 335 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 426 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 590 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 596 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 | 774 | Phosphotyrosine (by autocatalysis)(Potential). | Swiss-Prot 53.0 | 924 | Phosphotyrosine (by autocatalysis) (Bysimilarity). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr7 |
Promoter: 100262579 - 100264579 | Agilent_014791 |
chr7 |
Promoter: 100262579 - 100264579 | GoldenGate_Methylation_Cancer_Panel_I |
chr7 |
Promoter: 100262579 - 100264579 | GSE27584 |
chr7 |
Promoter: 100262579 - 100264579 | Agilent_014791_44K |