Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

2132

Name

EXT2

Synonymous

SOTV;exostosin glycosyltransferase 2;EXT2;exostosin glycosyltransferase 2

Definition

N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase|exostosin-2|glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase|multiple exostoses protein 2|putative tumor suppressor pr

Position

11p12-p11

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

EXT2(h) --> exostosin-2-isoform1(h) (expression).
exostosin-2(h) + MPSK(h) <==> exostosin-2(h):MPSK(h) (binding)
fabp4(h) + exostosin-2(h) <==> fabp4(h):exostosin-2(h) (binding)
exostosin-2(h) + gamma-synuclein(h) <==> exostosin-2(h):gamma-synuclein(h) (binding)
exostosin-2(h) + Orp150(h) <==> exostosin-2(h):Orp150(h) (binding)
HNF-4alpha(h) + exostosin-2(h) <==> HNF-4alpha(h):exostosin-2(h) (binding)
exostosin-2(h) + CNTF(h) <==> exostosin-2(h):CNTF(h) (binding)
exostosin-2(h) + elongin C(h) <==> exostosin-2(h):elongin C(h) (binding)
exostosin-2(h) + rps29(h) <==> exostosin-2(h):rps29(h) (binding)
exostosin-2(h) + CLEC2L(h) <==> exostosin-2(h):CLEC2L(h) (binding)
exostosin-2(h) + crb1(h) <==> exostosin-2(h):crb1(h) (binding)
EXT2(h) --> exostosin-2(h) (expression).
EXT2(h) --> exostosin-2-isoform2(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

288N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
637N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr11

Promoter: 44072175 - 44074175Agilent_014791

chr11

Promoter: 44072175 - 44074175GSE27584

chr11

Promoter: 44072175 - 44074175GSE27584

chr11

Promoter: 44072175 - 44074175Agilent_014791_44K


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