| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 23035 |
Name | PHLPP2 |
Synonymous | PHLPPL;PH domain and leucine rich repeat protein phosphatase 2;PHLPP2;PH domain and leucine rich repeat protein phosphatase 2 |
Definition | PH domain leucine-rich repeat-containing protein phosphatase 2 |
Position | 16q22.2 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
PHLPPL(h) --> phlpp2-isoform1(h) (expression). | phlpp2(h) --> AKT-1(h){pS473} (increase of phosphorylation) | phlpp2(h) --> AKT-3(h){p} (increase of phosphorylation) | phlpp2(h) + PKCbetaII(m.s.) <==> phlpp2(h):PKCbetaII(m.s.) (binding) | phlpp2(h) --/ PKCbeta(h) (decrease of abundance) | phlpp2(h) --/ PKCalpha(h) (decrease of abundance) | phlpp2(h) --/ PKCdelta(h) (decrease of abundance) | phlpp2(h) --/ PKCepsilon(h) (decrease of abundance) | PHLPPL(h) --> phlpp2(h) (expression). | Abl(h) --/ phlpp2(h) (decrease of abundance) | PKCbetaII(m.s.){p} --phlpp2(h)--> PKCbetaII(m.s.) + p (dephosphorylation) | PHLPPL(h) --> phlpp2-isoform3(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for PHLPP2 | |||
Methylation Profile [Top] | ||
There is no record for PHLPP2 | ||