Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

231

Name

AKR1B1

Synonymous

ADR|ALDR1|ALR2|AR;aldo-keto reductase family 1, member B1 (aldose reductase);AKR1B1;aldo-keto reductase family 1, member B1 (aldose reductase)

Definition

Lii5-2 CTCL tumor antigen|aldehyde reductase 1|aldo-keto reductase family 1 member B1|aldose reductase|low Km aldose reductase

Position

7q35

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

AKR1B1(h) --> aldose reductase(h) (expression).
TFEA(h) + aldose reductase(h) <==> TFEA(h):aldose reductase(h) (binding)
AKR1B1(h) --> aldose reductase(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

2N-acetylalanine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 133793928 - 133795928Agilent_014791

chr7

Promoter: 133793928 - 133795928GSE27584

chr7

Promoter: 133793928 - 133795928Agilent_014791_44K


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