Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

249

Name

ALPL

Synonymous

AP-TNAP|APTNAP|HOPS|TNAP|TNSALP;alkaline phosphatase, liver/bone/kidney;ALPL;alkaline phosphatase, liver/bone/kidney

Definition

alkaline phosphatase liver/bone/kidney isozyme|alkaline phosphatase, tissue-nonspecific isozyme|alkaline phosphomonoesterase|glycerophosphatase|liver/bone/kidney-type alkaline phosphatase|tissue-nonspecific ALP

Position

1p36.12

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

ALPL(h) --> TNSALP(h) (expression).
ALPL(h) --> TNSALP(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

140N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
230N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
271N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
303N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
430N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
502GPI-anchor amidated serine (Probable).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 21706945 - 21708945Agilent_014791

chr1

Promoter: 21706945 - 21708945GoldenGate_Methylation_Cancer_Panel_I

chr1

Promoter: 21706945 - 21708945GSE27584

chr1

Promoter: 21706945 - 21708945Agilent_014791_44K


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