Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3621

Name

ING1

Synonymous

p24ING1c|p33|p33ING1|p33ING1b|p47|p47ING1a;inhibitor of growth family, member 1;ING1;inhibitor of growth family, member 1

Definition

growth inhibitor ING1|growth inhibitory protein ING1|inhibitor of growth protein 1|tumor suppressor ING1

Position

13q34

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

SIRT1(h) + ING1b(h) <==> SIRT1(h):ING1b(h) (binding)
ING1b(h) + p53(h) <==> ING1b(h):p53(h) (binding)
ER-alpha(h) + ING1b(h) <==> ER-alpha(h):ING1b(h) (binding)
ING1b(h) + RbAp48(h) + SAP30(h) + HDAC1(h) + sin3a(h) + p40(h) <==> ING1b(h):RbAp48(h):SAP30(h):HDAC1(h):sin3a(h):p40(h) (binding)
ING1b(h) + HDAC1(h) + sin3a(h) + p40(h) <==> ING1b(h):HDAC1(h):sin3a(h):p40(h) (binding)
ING1b(h) + p16INK4a-p14(h) <==> ING1b(h):p16INK4a-p14(h) (binding)
ING1b(h) --> ING1b(h) (translocation)
ING1b(h) --> p21Cip1(m) (increase of abundance)
ING1b(h) --> mdm2(m) (increase of abundance)
ING1b(h) --> p53(m) (increase of abundance)
CBP(h) + ING1b(h) <==> CBP(h):ING1b(h) (binding)
p300(h) + ING1b(h) <==> p300(h):ING1b(h) (binding)
BCAA(m.s.) + ING1b(h) <==> BCAA(m.s.):ING1b(h) (binding)
ING1b(h) + HDAC1(m.s.) <==> ING1b(h):HDAC1(m.s.) (binding)
SIRT1(m.s.) + ING1b(h) <==> SIRT1(m.s.):ING1b(h) (binding)
ING1b(h) + RBBP1(m.s.) <==> ING1b(h):RBBP1(m.s.) (binding)
ING1(h) --> ING1b(h) (expression).
ING1b(h) --> ING1b(h) (translocation)
ING1(h) --/ AFP(h) (DNA binding; transrepression).
ING1(h) + p16INK4a-p14(h) <==> ING1(h):p16INK4a-p14(h) (binding)
trrap(h) + ING1(h) <==> trrap(h):ING1(h) (binding)
p/CAF(h) + ING1(h) <==> p/CAF(h):ING1(h) (binding)
CBP(h) + ING1(h) <==> CBP(h):ING1(h) (binding)
ING1(h) --> ING1(h) (expression).
CBP(h) + ING1a(h) <==> CBP(h):ING1a(h) (binding)
HDAC1(h) + ING1a(h) <==> HDAC1(h):ING1a(h) (binding)
ING1(h) --> ING1a(h) (expression).
ING1(h) --> ING1-isoform5(h) (expression).
ING1(h) --> ING1-isoform4(h) (expression).
ING1c(h) + HDAC1(m.s.) <==> ING1c(h):HDAC1(m.s.) (binding)
ING1c(h) + SIRT1(m.s.) <==> ING1c(h):SIRT1(m.s.) (binding)
ING1(h) --> ING1c(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for ING1

Methylation Profile   [Top]

Chromosome

Location

Source

chr13

Promoter: 110163860 - 110165860Agilent_014791

chr13

Promoter: 110162111 - 110164111Agilent_014791

chr13

Promoter: 110162126 - 110164126GSE27584

chr13

Promoter: 110162111 - 110164111GSE27584

chr13

Promoter: 110161584 - 110163584GSE27584

chr13

Promoter: 110163860 - 110165860GSE27584

chr13

Promoter: 110161584 - 110163584Agilent_014791_44K


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