General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information |
|
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Gene ID | 3685 |
Name | ITGAV |
Synonymous | CD51|MSK8|VNRA|VTNR;integrin, alpha V;ITGAV;integrin, alpha V |
Definition | antigen identified by monoclonal antibody L230|integrin alpha-V|integrin alphaVbeta3|integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)|vitronectin receptor subunit alpha |
Position | 2q31-q32 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] |
Transcription Factors [Top] |
Regulation From TransFac database |
CD51(h) + beta6-integrin(h) + LAP3(h) <==> CD51(h):beta6-integrin(h):LAP3(h) (binding) | LAP1(mo) + CD51(h) + beta1-integrin(h) <==> LAP1(mo):CD51(h):beta1-integrin(h) (binding) | LAP1(mo) + CD51(h) + beta5-integrin(h) <==> LAP1(mo):CD51(h):beta5-integrin(h) (binding) | LAP1(mo) + CD51(h) <==> LAP1(mo):CD51(h) (binding) | LAP1(h) + CD51(h) + beta1-integrin(h) <==> LAP1(h):CD51(h):beta1-integrin(h) (binding) | LAP1(h) + CD51(h) + beta3-integrin(h) <==> LAP1(h):CD51(h):beta3-integrin(h) (binding) | LAP1(h) + CD51(h) + beta5-integrin(h) <==> LAP1(h):CD51(h):beta5-integrin(h) (binding) | LAP1(h) + CD51(h) + beta6-integrin(h) <==> LAP1(h):CD51(h):beta6-integrin(h) (binding) | Cas(h) + EGFR(h) + CD51(h) + beta3-integrin(h) + Src(h) <==> Cas(h):EGFR(h):CD51(h):beta3-integrin(h):Src(h) (binding) | CAML1(m.s.) + CD51(h) <==> CAML1(m.s.):CD51(h) (binding) | CD51(h) + aup-1-isoformS(h) <==> CD51(h):aup-1-isoformS(h) (binding) | ITGAV(h) --> CD51(h) (expression). | beta3-integrin(h) + CD51-isoform1(h) <==> beta3-integrin(h):CD51-isoform1(h) (binding) | ITGAV(h) --> CD51-isoform1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
Location (AA) |
PTM type |
Literature |
Database |
74 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 290 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 296 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 488 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 554 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 615 | N-linked (GlcNAc...). | Swiss-Prot 53.0 | 704 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 835 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 851 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 874 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 945 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 973 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 980 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
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Methylation Profile [Top] | ||
Chromosome |
Location |
Source |
---|---|---|
chr2 |
Promoter: 187161545 - 187163545 | Agilent_014791 |
chr2 |
Promoter: 187161545 - 187163545 | GSE27584 |
chr2 |
Promoter: 187161545 - 187163545 | Agilent_014791_44K |