Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4486

Name

MST1R

Synonymous

CD136|CDw136|PTK8|RON;macrophage stimulating 1 receptor;MST1R;macrophage stimulating 1 receptor

Definition

MSP receptor|MST1R variant RON30|MST1R variant RON62|PTK8 protein tyrosine kinase 8|RON variant 21|RON variant E2E3|c-met-related tyrosine kinase|macrophage stimulating 1 receptor (c-met-related tyrosine kinase)|macrophage-stimulating protein receptor|p18

Position

3p21.3

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for MST1R

Transcription Factors   [Top]

Regulation From TransFac database

STAT1alpha(h) + RON(h) <==> STAT1alpha(h):RON(h) (binding)
STAT1beta(h) + RON(h) <==> STAT1beta(h):RON(h) (binding)
RON(h) + STAT5B(h) <==> RON(h):STAT5B(h) (binding)
MST1R(h) --> RON(h) (expression).
MST1R(h) --> RON(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

66N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
419N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
458N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
488N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
654N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
720N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
841N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
897N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
1353Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
1360Phosphotyrosine (by autocatalysis) (Bysimilarity).Swiss-Prot 53.0
1353Phosphotyrosine (Ron)10871856Phospho.ELM 6.0
1360Phosphotyrosine (Ron)10871856Phospho.ELM 6.0
1238Phosphotyrosine (Ron)10871856Phospho.ELM 6.0
1239Phosphotyrosine (Ron)10871856Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 49915574 - 49917574Agilent_014791

chr3

Promoter: 49915574 - 49917574GoldenGate_Methylation_Cancer_Panel_I

chr3

Promoter: 49915574 - 49917574GSE27584

chr3

Promoter: 49915574 - 49917574Agilent_014791_44K


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