Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

4627

Name

MYH9

Synonymous

BDPLT6|DFNA17|EPSTS|FTNS|MHA|NMHC-II-A|NMMHC-IIA|NMMHCA;myosin, heavy chain 9, non-muscle;MYH9;myosin, heavy chain 9, non-muscle

Definition

cellular myosin heavy chain, type A|myosin-9|non-muscle myosin heavy chain A|non-muscle myosin heavy chain IIa|non-muscle myosin heavy polypeptide 9|nonmuscle myosin heavy chain II-A

Position

22q13.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

MYH9(h) --> Myosin-9(h) (expression).
Myosin-9(h) + cxcr4(m.s.) <==> Myosin-9(h):cxcr4(m.s.) (binding)
cxcr4(h) + MLC(h) + Myosin-9(h) <==> cxcr4(h):MLC(h):Myosin-9(h) (binding)
cxcr4(h) + Myosin-9(h) + MLC(h) + F-actin(h) <==> cxcr4(h):Myosin-9(h):MLC(h):F-actin(h) (binding)
Myosin-9(h) + cxcr4(h) <==> Myosin-9(h):cxcr4(h) (binding)
4.1R(h) + Myosin-9(h) <==> 4.1R(h):Myosin-9(h) (binding)
Myosin-9(h) + beta-catenin(x) <==> Myosin-9(h):beta-catenin(x) (binding)
MYH9(h) --> Myosin-9(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

2N-acetylalanine.Swiss-Prot 53.0
638Phosphothreonine (By similarity).Swiss-Prot 53.0
1943Phosphoserine.Swiss-Prot 53.0
1942Phosphoserine95021154;16083285;16094384;17081983Phospho.ELM 6.0
1915Phosphoserine (PKC alpha;PK)91113708;9545325Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr22

Promoter: 35113427 - 35115427Agilent_014791

chr22

Promoter: 35113427 - 35115427GSE27584

chr22

Promoter: 35113427 - 35115427Agilent_014791_44K


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