Entrez Gene

Basic Information
Gene ID	4734
Name	NEDD4
Synonymous	NEDD4-1\|RPF1;neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase;NEDD4;neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
Definition	E3 ubiquitin-protein ligase NEDD4\|cell proliferation-inducing gene 53 protein\|neural precursor cell expressed developmentally down-regulated protein 4\|receptor-potentiating factor 1
Position	15q
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
NEDD4-1(h) + SGK-1(h) <==> NEDD4-1(h):SGK-1(h) (binding)
alphaENaC(h) + NEDD4-1(h) <==> alphaENaC(h):NEDD4-1(h) (binding)
NEDD4(h) --> NEDD4-1(h) (expression).
NEDD4-1(h) + n ubiquitin(h) --Ubc5A(m.s.)--> NEDD4-1(h){ub(n)} (ubiquitination)
NEDD4(h) --> NEDD4-1(h) (expression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
329	Phosphothreonine (By similarity).	Swiss-Prot 53.0
351	Phosphoserine (By similarity).	Swiss-Prot 53.0