Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

Name

Synonymous

;;;

Definition

Position

Gene Type

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

There is no record for

Transcription Factors   [Top]

Regulation From TransFac database

NF-AT2(h) --> Il2(m) (DNA binding).
NF-AT2(h) --> Il4(m) (DNA binding).
NF-AT2(h) --> IL-5(m) (DNA binding).
PPARgamma(h) + NF-AT2(h) <==> PPARgamma(h):NF-AT2(h) (binding)
calcineurin(h) + NF-AT2(h) <==> calcineurin(h):NF-AT2(h) (binding)
PKCzeta(v.s.) + NF-AT2(h) <==> PKCzeta(v.s.):NF-AT2(h) (binding)
ERK1(v.s.) + NF-AT2(h) <==> ERK1(v.s.):NF-AT2(h) (binding)
JNK3(v.s.) + NF-AT2(h) <==> JNK3(v.s.):NF-AT2(h) (binding)
p38alpha(v.s.) + NF-AT2(h) <==> p38alpha(v.s.):NF-AT2(h) (binding)
NF-AT2(h) + ATP --ERK1(v.s.)--> NF-AT2(h){p} + ADP (phosphorylation)
NF-AT2(h) + ATP --JNK3(v.s.)--> NF-AT2(h){p} + ADP (phosphorylation)
NF-AT2(h) + ATP --p38alpha(v.s.)--> NF-AT2(h){p} + ADP (phosphorylation)
NF-AT2(h) + ATP --CKII-alpha(h):CKII-alpha2(h):(CKII-beta(h))2--> NF-AT2(h){p} + ADP (phosphorylation)
NF-AT2(h) + CKII-alpha(mo) <==> CKII-alpha(mo):NF-AT2(h) (binding)
NF-AT2(h) + NTP --PKAc(v.s.)--> NF-AT2(h){p} + NDP (phosphorylation)
NF-AT2(h) --> EGR3(h) (DNA binding; transactivation).
NF-AT2(h) --> IL2(h) (DNA binding; transactivation).
NF-AT2(h) --> IL-4(h) (DNA binding; transactivation).
NF-AT2(h) --> IFNG(h) (DNA binding; transactivation).
NF-AT2(h) --> PTGS2(h) (DNA binding; transactivation).
NF-AT2(h) --> FASLG(h) (DNA binding; transactivation)
Elf-1(h) + NF-AT2(h) <==> Elf-1(h):NF-AT2(h) (binding) [re.
SPI1(m.s.) + NF-AT2(h) <==> SPI1(m.s.):NF-AT2(h) (binding) [re.
c-Ets-1(m.s.) + NF-AT2(h) <==> c-Ets-1(m.s.):NF-AT2(h) (binding) [re.
NF-AT2(h) --> TNF(h) (transactivation)
NF-AT2(h) --> IL2(h) (transactivation)
NF-AT2(h) --> NF-AT2(h) (translocation) [re.
NF-AT2(h) --> ITGB3(h) (DNA binding).
NF-AT2(h) --> FCER2(h) (DNA binding).
NF-AT2(h) --> Mmp9(m) (DNA binding).
NF-AT2(h) --> Itgb3(m) (transactivation)
GATA-3(m) + NF-AT2(h) <==> GATA-3(m):NF-AT2(h) (binding)
NF-AT2(h) --> F3(h) (DNA binding).
NF-AT2(h) --> Nfatc1(m) (transactivation)
NF-AT2(h) --> IL-2Ralpha(m) (transactivation)
NF-AT2(h) --> c-myc(h) (DNA binding; transactivation).
NF-AT2(h) --> IL-5(h) (DNA binding).
NF-AT2(h) --> CD40LG(h) (DNA binding).
NF-AT2(h) --> IL17A(h) (DNA binding).
NF-AT2(h) --> CTLA4(h) (DNA binding).
NF-AT2(h) --> Ptgs2(r) (DNA binding; transactivation).
NF-AT2(h) --> TNFSF14(h) (DNA binding).
NFATC1(h) --> NF-AT2(h) (expression).
NF-AT2(h){p} --calcineurin(v.s.)--> NF-AT2(h) + p (dephosphorylation)
NF-AT2(h) --> NF-AT2(h) (translocation) [re.
NFATC1(h) --> NFAT2A-beta(h) (expression).
NFAT2A-alpha(h) + JNK1(h) <==> NFAT2A-alpha(h):JNK1(h) (binding)
NFAT2A-alpha(h) + CRM1(h) <==> NFAT2A-alpha(h):CRM1(h) (binding)
NFAT2A-alpha(h) + Elf-1(m.s.) <==> NFAT2A-alpha(h):Elf-1(m.s.) (binding) [re.
NFAT2A-alpha(h){pS172} --calcineurin(r)--> NFAT2A-alpha(h) + p (dephosphorylation)
NFATC1(h) --> NFAT2A-alpha(h) (expression).
NFAT2C-alpha(h) --> IL2(h) (DNA binding).
NFATC1(h) --> NFAT2C-alpha(h) (expression).
NFATC1(h) --> NFAT2-B-alpha(h) (expression).
NFATC1(h) --> NFAT2-B-beta(h) (expression).
NFATC1(h) --> NFAT2-C-beta(h) (expression).
NFATC1(h) --> NFAT2-C-alpha-prime(h) (expression).
NFATC1(h) --> NFAT2-A-alpha-prime(h) (expression).
NFATC1(h) --> NFAT2-B-alpha-prime(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

117Phosphoserine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr18

Promoter: 75255260 - 75257260Agilent_014791

chr18

Promoter: 75259814 - 75261814Agilent_014791

chr18

Promoter: 75255260 - 75257260GSE27584

chr18

Promoter: 75259814 - 75261814GSE27584

chr18

Promoter: 75259814 - 75261814GSE27584

chr18

Promoter: 75255260 - 75257260GSE27584

chr18

Promoter: 75255260 - 75257260GSE27584

chr18

Promoter: 75255260 - 75257260Agilent_014791

chr18

Promoter: 75259814 - 75261814Agilent_014791


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