Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

51196

Name

PLCE1

Synonymous

NPHS3|PLCE|PPLC;phospholipase C, epsilon 1;PLCE1;phospholipase C, epsilon 1

Definition

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1|PLC-epsilon-1|pancreas-enriched phospholipase C|phosphoinositide phospholipase C-epsilon-1|phosphoinositide-specific phospholipase C epsilon-1

Position

10q23

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

PLCepsilon1(h) + Rap2B(h) <==> PLCepsilon1(h):Rap2B(h) (binding)
PLCE1(h) --> PLCepsilon1(h) (expression).
PIP2 --PLCepsilon1(h)--> DAG + IP3 (hydrolysis)
PLCepsilon1(h) + Rap1A(h):GTP <==> PLCepsilon1(h):Rap1A(h):GTP (binding)
PLCepsilon1(h) + H-Ras(h):GTP <==> PLCepsilon1(h):H-Ras(h):GTP (binding)
PLCepsilon1(h) --> PLCepsilon1(h) (translocation)
PLCepsilon1(h) --> PLCepsilon1(h) (translocation)
PLCE1(h) --> PLCepsilon1(h) (expression).
PLCepsilon1(h) --> PLCepsilon1(h) (translocation)
PLCepsilon1(h) --> PLCepsilon1(h) (translocation)
PIP2 --PLCepsilon1(h)--> DAG + IP3 (hydrolysis)

Post Transcriptional Modification   [Top]

There is no record for PLCE1

Methylation Profile   [Top]

There is no record for PLCE1



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