Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5516

Name

PPP2CB

Synonymous

PP2Abeta|PP2CB;protein phosphatase 2, catalytic subunit, beta isozyme;PPP2CB;protein phosphatase 2, catalytic subunit, beta isozyme

Definition

PP2A-beta|protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform|protein phosphatase 2, catalytic subunit, beta isoform|protein phosphatase 2A catalytic subunit, beta isoform|protein phosphatase type 2A catalytic subunit|serine/threonine pro

Position

8p12

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

PPP2CB(h) --> PP2ACbeta(h) (expression).
PP2ACbeta(h) + NR3A(m.s.) <==> PP2ACbeta(h):NR3A(m.s.) (binding)
MST-3(h) + PP2ACbeta(h) <==> MST-3(h):PP2ACbeta(h) (binding)
PP4C(h) + PP2ACbeta(h) <==> PP4C(h):PP2ACbeta(h) (binding)
PPP2CB(h) --> PP2ACbeta(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

307Phosphotyrosine.Swiss-Prot 53.0
309Leucine methyl ester.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 30789394 - 30791394Agilent_014791

chr8

Promoter: 30789394 - 30791394GSE27584

chr8

Promoter: 30789394 - 30791394GSE27584

chr8

Promoter: 30789394 - 30791394Agilent_014791_44K

chr8

Promoter: 30789394 - 30791394Agilent_014791


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