Entrez Gene

Basic Information
Gene ID	5563
Name	PRKAA2
Synonymous	AMPK\|AMPK2\|AMPKa2\|PRKAA;protein kinase, AMP-activated, alpha 2 catalytic subunit;PRKAA2;protein kinase, AMP-activated, alpha 2 catalytic subunit
Definition	5'-AMP-activated protein kinase catalytic subunit alpha-2\|5'-AMP-activated protein kinase, catalytic alpha-2 chain\|ACACA kinase\|AMP-activated protein kinase alpha-2 subunit variant 2\|AMP-activated protein kinase alpha-2 subunit variant 3\|AMPK alpha 2\|AMPK
Position	1p31
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
AMPKalpha-2(h) + PPARalpha(m) <==> AMPKalpha-2(h):PPARalpha(m) (binding)
AMPKalpha-2(h) --> AMPKalpha-2(h) (translocation)
AMPKalpha-2(h) + ATP --> AMPKalpha-2(h){pT172} + ADP (phosphorylation)
PRKAA2(h) --> AMPKalpha-2(h) (expression).
AMPKalpha-2(h) --> AMPKalpha-2(h) (translocation)
AMPKalpha-2(h) --> eNOS(h){pS633} (increase of phosphorylation)
AMPKalpha-2(h) + ATP --> AMPKalpha-2(h){pT172} + ADP (phosphorylation)
PRKAA2(h) --> AMPKalpha-2(h) (expression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
172	Phosphothreonine (by STK11) (Bysimilarity).	Swiss-Prot 53.0
173	Phosphoserine (By similarity).	Swiss-Prot 53.0
500	Phosphoserine (By similarity).	Swiss-Prot 53.0