Entrez Gene

Basic Information
Gene ID	5629
Name	PROX1
Synonymous	-;prospero homeobox 1;PROX1;prospero homeobox 1
Definition	homeobox prospero-like protein PROX1\|prospero homeobox protein 1\|prospero-related homeobox 1
Position	1q41
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
prox1(h) --> SIX3(h) (transactivation)
LRH-1(h) + prox1(h) <==> LRH-1(h):prox1(h) (binding)
prox1(h) --/ CYP7A1(h) (transrepression)
HNF-4alpha(h) + prox1(h) <==> HNF-4alpha(h):prox1(h) (binding)
PPARdelta(h) + prox1(h) <==> PPARdelta(h):prox1(h) (binding)
RORalpha(h) + prox1(h) <==> RORalpha(h):prox1(h) (binding)
ERR1(h) + prox1(h) <==> ERR1(h):prox1(h) (binding)
ERR3(h) + prox1(h) <==> ERR3(h):prox1(h) (binding)
MR(h) + prox1(h) <==> MR(h):prox1(h) (binding)
PROX1(h) --> prox1(h) (expression).
prox1-xbb1(h) + pax6(z) <==> prox1-xbb1(h):pax6(z) (binding)
prox1-xbb1(h) --> CRY-betB1(c) (DNA binding; transactivation).
prox1-xbb1(h) --> FGFR3(m) (DNA binding; transactivation).
PROX1(h) --> prox1-xbb1(h) (expression).
PROX1(h) --> prox1-isoform1(h) (expression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
177	Phosphoserine (By similarity).	Swiss-Prot 53.0
179	Phosphoserine (By similarity).	Swiss-Prot 53.0
291	Phosphoserine (By similarity).	Swiss-Prot 53.0
511	Phosphoserine (By similarity).	Swiss-Prot 53.0
514	Phosphoserine (By similarity).	Swiss-Prot 53.0