| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 581 |
Name | BAX |
Synonymous | BCL2L4;BCL2-associated X protein;BAX;BCL2-associated X protein |
Definition | BCL2-associated X protein omega|Baxdelta2G9|Baxdelta2G9omega|Baxdelta2omega|apoptosis regulator BAX|bcl-2-like protein 4|bcl2-L-4 |
Position | 19q13.3-q13.4 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
Bcl-2(h) + Bax(h) <==> Bcl-2(h):Bax(h) (binding) | Bcl-X(h) + Bax(h) <==> Bcl-X(h):Bax(h) (binding) | vdac1(h) + Bax(h) <==> Bax(h):vdac1(h) (binding; assembly) | Bcl-B(h) + Bax(h) <==> Bcl-B(h):Bax(h) (binding) | 2 Bax(h) <==> Bax(h):Bax(h) (oligomerization) | Bid(m) + Bax(h) <==> Bid(m):Bax(h) (binding) | BimS(h) + Bax(h) <==> BimS(h):Bax(h) (binding) | BimAD(h) + Bax(h) <==> BimAD(h):Bax(h) (binding) | 14-3-3tau(h) + Bax(h) <==> 14-3-3tau(h):Bax(h) (binding) | 14-3-3epsilon(h) + Bax(h) <==> 14-3-3epsilon(h):Bax(h) (binding) | 14-3-3zeta(h) + Bax(h) <==> 14-3-3zeta(h):Bax(h) (binding) | 14-3-3zeta(b) + Bax(h) <==> 14-3-3zeta(b):Bax(h) (binding) | Endophilin B1(h) + Bax(h) <==> Endophilin B1(h):Bax(h) (binding) | Bcl-2(h){pS70} + Bax(h) <==> Bcl-2(h){pS70}:Bax(h) (binding) | Ku70(h) + Bax(h) <==> Ku70(h):Bax(h) (binding) | Bax(h) + ATP --AKT(m.s.){p}--> Bax(h){p} + ADP (phosphorylation) | Bax(h) + PKCepsilon(h) <==> Bax(h):PKCepsilon(h) (binding) | Bak(h) + Bax(h) <==> Bak(h):Bax(h) (binding) | Bax(h) + PKCepsilon(m) <==> Bax(h):PKCepsilon(m) (binding) | Bax(h) --> Bax-p18(h) (cleavage) | Bax(h) --> Bax(h) (translocation) | Bax(h) + vdac1(h) <==> Bax(h):vdac1(h) (binding) | Bax(h) + Bak(m.s.) <==> Bax(h):Bak(m.s.) (binding) | Bax(h) + p53(h) <==> Bax(h):p53(h) (binding) | 3 Bax(h) <==> (Bax(h))3 (oligomerization) | Bax(h) + BimS(m) <==> Bax(h):BimS(m) (binding) | Mcl-1(h) + Bax(h) <==> Mcl-1(h):Bax(h) (binding) | Bax(h) + tBid(h) <==> Bax(h):tBid(h) (binding) | Bax(h) --> protein remnants (degradation) | Bax(h) + 3 ATP --> Bax(h){pS60}{pS163}{pS184} + 3 ADP (phosphorylation) | brca1(h) --/ Bax(h) (inhibition) | BAX(h) --> Bax(h) (expression). | P2RX7(h) --> Bax(h) (decrease of abundance) | p53-isoform1(h) --> Bax(h) (increase of abundance) | Bax(h) --> Bax(h) (translocation) | p53-isoform1(h){pS315} --> Bax(h) (increase of abundance) | RNF96(h) --/ Bax(h) (decrease of abundance) | MULE(h) --/ Bax(h) (decrease of abundance) | mdm2(h) --/ Bax(h) (decrease of abundance) | p16INK4a-xbb1(h) --> Bax(h) (increase of abundance) | Cdc6-p49(h) --> Bax(h) (increase of abundance) | Cdc6-p32(h) --> Bax(h) (increase of abundance) | p53(m.s.) --> Bax(h) (increase of abundance) | p75NTR(m.s.) --> Bax(h) (increase of abundance) | YAP(m.s.) --> Bax(h) (increase of abundance) | NDKA(h) --> Bax(h) (increase of abundance) | STRAP(h) --> Bax(h) (increase of abundance) | GIF(m.s.) --/ Bax(h) (decrease of abundance) | GIF(h) --/ Bax(h) (decrease of abundance) | pdcd5(h) --> Bax(h) (increase of abundance) | slc5a3(h) --> Bax(h) (increase of abundance) | Apak(h) --/ Bax(h) (decrease of abundance) | EIF5A1-isoform1(h) --> Bax(h) (increase of abundance) | Cytochrome C(r) --tBid(m),Bax(h)--> Cytochrome C(r) (translocation) | Bax-sigma(h) + Bax-alpha(h) <==> Bax-sigma(h):Bax-alpha(h) (binding) | Bax-sigma(h) + Bok(h) <==> Bax-sigma(h):Bok(h) (binding) | Bax-sigma(h) + Bak(h) <==> Bax-sigma(h):Bak(h) (binding) | Bax-sigma(h) + A1(h) <==> Bax-sigma(h):A1(h) (binding) | Bax-sigma(h) + Bcl-X(h) <==> Bax-sigma(h):Bcl-X(h) (binding) | 2 Bax-sigma(h) <==> (Bax-sigma(h))2 (binding) | BAX(h) --> Bax-sigma(h) (expression). | Bax-sigma(h) + Bax-alpha(h) <==> Bax-sigma(h):Bax-alpha(h) (binding) | Bax-alpha(h) + ATP --GSK3beta(m.s.)--> Bax-alpha(h){pS163} + ADP (phosphorylation) | BAX(h) --> Bax-alpha(h) (expression). | BAX(h) --> Bax-beta(h) (expression). | BAX(h) --> Bax-gamma(h) (expression). | BAX(h) --> Bax-delta(h) (expression). | BAX(h) --> Bax-epsilon(h) (expression). | BAX(h) --> Bax-zeta(h) (expression). | BAX(h) --> Bax-psi(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for BAX | |||
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr19 |
Promoter: 54148429 - 54150429 | Agilent_014791 |
chr19 |
Promoter: 54148429 - 54150429 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 54148429 - 54150429 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 54148429 - 54150429 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 54148429 - 54150429 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 54148429 - 54150429 | GoldenGate_Methylation_Cancer_Panel_I |
chr19 |
Promoter: 54148429 - 54150429 | GSE27584 |
chr19 |
Promoter: 54148429 - 54150429 | GSE27584 |
chr19 |
Promoter: 54148429 - 54150429 | GSE27584 |
chr19 |
Promoter: 54148429 - 54150429 | GSE27584 |
chr19 |
Promoter: 54148429 - 54150429 | Agilent_014791_44K |
chr19 |
Promoter: 54148429 - 54150429 | Agilent_014791 |