Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

58508

Name

KMT2C

Synonymous

HALR|MLL3;lysine (K)-specific methyltransferase 2C;KMT2C;lysine (K)-specific methyltransferase 2C

Definition

ALR-like protein|histone-lysine N-methyltransferase 2C|histone-lysine N-methyltransferase MLL3|histone-lysine N-methyltransferase, H3 lysine-4 specific|homologous to ALR protein|myeloid/lymphoid or mixed-lineage leukemia protein 3

Position

7q36.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog(h) --> rbbp5(h) (binding)
adenylate kinase isoenzyme 1(h) + myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog(h) <==> adenylate kinase isoenzyme 1(h):myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog(h) (binding)
MLL3(h) --> myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog(h) (expression).
MLL3(h) --> myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog isoform-1(h) (expression).
MLL3(h) --> myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog isoform-2(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

2809N6-acetyllysine.Swiss-Prot 53.0
4018Phosphotyrosine.Swiss-Prot 53.0
4022Phosphoserine.Swiss-Prot 53.0
4018Phosphotyrosine17081983Phospho.ELM 6.0
4022Phosphoserine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

There is no record for KMT2C



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