Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6091

Name

ROBO1

Synonymous

DUTT1|SAX3;roundabout, axon guidance receptor, homolog 1 (Drosophila);ROBO1;roundabout, axon guidance receptor, homolog 1 (Drosophila)

Definition

deleted in U twenty twenty|roundabout homolog 1

Position

3p12

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

ROBO1(h) --> DUTT1-isoform1(h) (expression).
ROBO1(h) --> DUTT1(h) (expression).
ROBO1(h) --> DUTT1-isoform2(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

160N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
463N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
790N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
820N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
827N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
940Phosphoserine.Swiss-Prot 53.0
1038Phosphotyrosine; by ABL; in vitro.Swiss-Prot 53.0
1073Phosphotyrosine; by ABL; in vitro.Swiss-Prot 53.0
1114Phosphotyrosine; by ABL; in vitro.Swiss-Prot 53.0
1240Phosphothreonine.Swiss-Prot 53.0
940Phosphoserine17081983Phospho.ELM 6.0
1240Phosphothreonine17081983Phospho.ELM 6.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr3

Promoter: 79150764 - 79152764Agilent_014791

chr3

Promoter: 79150764 - 79152764GSE27584

chr3

Promoter: 79721251 - 79723251PMID:12615722

chr3

Promoter: 79150764 - 79152764PMID:12615722

chr3

Promoter: 79721251 - 79723251PMID:12082532

chr3

Promoter: 79150764 - 79152764PMID:12082532


')