Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6387

Name

CXCL12

Synonymous

IRH|PBSF|SCYB12|SDF1|TLSF|TPAR1;chemokine (C-X-C motif) ligand 12;CXCL12;chemokine (C-X-C motif) ligand 12

Definition

intercrine reduced in hepatomas|pre-B cell growth-stimulating factor|stromal cell-derived factor 1

Position

10q11.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

cxcr4(h) + SDF-1alpha(h) <==> cxcr4(h):SDF-1alpha(h) (binding)
SDF-1alpha(h) + cxcr4(h) <==> SDF-1alpha(h):cxcr4(h) (binding)
CXCL12(h) --> SDF-1alpha(h) (expression).
CXCL12(h) --> SDF-1beta(h) (expression).
adiponectin(h) + SDF-1(h) <==> adiponectin(h):SDF-1(h) (binding)
adiponectin(m) + SDF-1(h) <==> adiponectin(m):SDF-1(h) (binding)
SDF-1(h) + cxcr4(h) <==> SDF-1(h):cxcr4(h) (binding)
heparin + SDF-1(h) <==> heparin:SDF-1(h) (binding)
SDF-1(h) --> MMP9(h) (transactivation)
CXCL12(h) --> SDF-1(h) (expression).
CXCL12(h) --> SDF1_01(h) (expression).
hsa-miR-23a --/ SDF1_01(h) (predicted)
hsa-miR-23b --/ SDF1_01(h) (predicted)
CXCL12(h) --> SDF1_02(h) (expression).
hsa-miR-23a --/ SDF1_02(h) (predicted)
hsa-miR-23b --/ SDF1_02(h) (predicted)

Post Transcriptional Modification   [Top]

There is no record for CXCL12

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 44200048 - 44202048Agilent_014791

chr10

Promoter: 44200048 - 44202048GSE27584

chr10

Promoter: 44200048 - 44202048GSE27584

chr10

Promoter: 44200048 - 44202048GSE27584


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