| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 64682 |
Name | ANAPC1 |
Synonymous | APC1|MCPR|TSG24;anaphase promoting complex subunit 1;ANAPC1;anaphase promoting complex subunit 1 |
Definition | anaphase-promoting complex 1 (meiotic checkpoint regulator)|anaphase-promoting complex subunit 1|cyclosome subunit 1|mitotic checkpoint regulator|testis-specific gene 24 protein |
Position | 2q12.1 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
APC1(h) + ATP --plk1(h)--> APC1(h){pT520} + ADP (phosphorylation) | APC1(h) + ATP --plk1(h)--> APC1(h){pS547} + ADP (phosphorylation) | APC1(h) + ATP --plk1(h)--> APC1(h){pS688} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pT291} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pS355} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pS364} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pS377} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pT530} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pT537} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pS547} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pS555} + ADP (phosphorylation) | APC1(h) + ATP --cyclinB1(h):Cdk1(h):Cks1(h)--> APC1(h){pS688} + ADP (phosphorylation) | Emi1(h) + APC1(h) + Cdc27(h) + Cdc16(h) <==> Emi1(h):APC1(h):Cdc27(h):Cdc16(h) (binding) | APC1(h) + APC11(h) + APC2(h) + APC4(h) + APC5(h) + APC7(h) + Cdc16(h) + Cdc23(h) + Emi1(h) + Fzr1(h) <==> APC1(h):APC2(h):APC4(h):APC5(h):Cdc16(h):APC7(h):Cdc23(h):APC11(h):Fzr1(h):Emi1(h) (binding) | APC1(h) + Emi1(h) <==> APC1(h):Emi1(h) (binding) | APC1(h) + APC2(h) + APC4(h) + APC5(h) + APC11(h) <==> APC1(h):APC2(h):APC4(h):APC5(h):APC11(h) (binding) | ANAPC1(h) --> APC1(h) (expression). | ANAPC1(h) --> APC1(h) (expression). |
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Post Transcriptional Modification [Top] | |||
There is no record for ANAPC1 | |||
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr2 |
Promoter: 112357712 - 112359712 | Agilent_014791 |
chr2 |
Promoter: 112357712 - 112359712 | GSE27584 |
chr2 |
Promoter: 112357712 - 112359712 | Agilent_014791_44K |