| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
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|---|---|
Gene ID | 650 |
Name | BMP2 |
Synonymous | BDA2|BMP2A;bone morphogenetic protein 2;BMP2;bone morphogenetic protein 2 |
Definition | BMP-2A|bone morphogenetic protein 2A |
Position | 20p12 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
BMP2A(h) + Drm(x) <==> BMP2A(h):Drm(x) (binding) | BMP2A(h) + Drm(h) <==> BMP2A(h):Drm(h) (binding) | BMP2A(h) + DAN(m) <==> BMP2A(h):DAN(m) (binding) | BMP2A(h) + Cer1(h) <==> BMP2A(h):Cer1(h) (binding) | BMP2A(h) + BMPR-II(h) + BMPR-IA(h) <==> BMP2A(h):BMPR-IA(h):BMPR-II(h) (binding) | BMP2A(h) + BMPR-IB(m) + BMPR-IA(h) <==> BMP2A(h):BMPR-IA(h):BMPR-IB(m) (binding) | BMP2A(h) + BMPR-IB(m) + BMPR-II(h) <==> BMP2A(h):BMPR-IB(m):BMPR-II(h) (binding) | BMP2A(h) --/ Nodal(c) (transrepression) | BMP2A(h) + chordin(x) <==> BMP2A(h):chordin(x) (binding) | BMP2A(h) + 2 BMPR-IB(m) <==> BMP2A(h):BMPR-IB(m):BMPR-IB(m) (binding) | BMP2A(h) + BMPR-IA(h):BMPR-IA(h) <==> BMP2A(h):BMPR-IA(h):BMPR-IA(h) (binding) | BMP2A(h) + BMPR-IA(h) <==> BMP2A(h):BMPR-IA(h) (binding) | BMP2A(h) + BMPR-II(h) <==> BMP2A(h):BMPR-II(h) (binding) | BMP2A(h) + ActR-II(h) <==> BMP2A(h):ActR-II(h) (binding) | BMP2A(h) + BMPR-IB(h) <==> BMP2A(h):BMPR-IB(h) (binding) | BMP2A(h) --> Smad1(m) (activation; phosphorylation) | BMP2A(h) + noggin(h) <==> BMP2A(h):noggin(h) (binding) | BMP2A(h) --> CDKN1A(h) (transactivation) | BMP2A(h) --> CDKN1B(h) (transactivation) | BMP2A(h) --/ pRb(h) (inhibition) | BMP2A(h) --/ BCL2L1(h) (transrepression) | BMP2A(h) --/ STAT3(h) (transrepression) | BMP2A(h) + Tkv(d) <==> BMP2A(h):Tkv(d) (binding) | BMP2A(h) + Daf-4(ce) + Tkv(d) <==> BMP2A(h):Daf-4(ce):Tkv(d) (binding) | BMP2A(h) --/ Fgf4(m) (transrepression) | BMP2A(h) --> Smad6(r) (increase of abundance) | BMP2(h) --> BMP2A(h) (expression). | BMP2A(h) --> RUNX2(m) (transactivation) | BMP2A(h) --> Zfp64(m) (transactivation) | BMP2A(h) --> Hey1(m) (transactivation) | BMP2(h) --> BMP2A(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
135 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 163 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 164 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 200 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr20 |
Promoter: 6695245 - 6697245 | Agilent_014791 |
chr20 |
Promoter: 6695245 - 6697245 | GoldenGate_Methylation_Cancer_Panel_I |
chr20 |
Promoter: 6695245 - 6697245 | GSE27584 |
chr20 |
Promoter: 6695245 - 6697245 | Agilent_014791_44K |
chr20 |
Promoter: 6695245 - 6697245 | Agilent_014791 |
chr20 |
Promoter: 6695245 - 6697245 | PMID:16314833 |
chr20 |
Promoter: 6695245 - 6697245 | PMID:15342377 |