Entrez Gene

Basic Information
Gene ID	6672
Name	SP100
Synonymous	lysp100b;SP100 nuclear antigen;SP100;SP100 nuclear antigen
Definition	SP100-HMG nuclear autoantigen\|nuclear autoantigen Sp-100\|nuclear dot-associated Sp100 protein\|speckled 100 kDa
Position	2q37.1
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
Sp100(h) + DRI1(m) <==> DRI1(m):Sp100(h) (binding)
c-Ets-1(h) + Sp100(h) <==> c-Ets-1(h):Sp100(h) (binding)
Sp100(h) + sumo1(h) --> Sp100(h){sumo} (sumoylation)
Sp100(h) --> Sp100(h) (translocation)
Sp100(h) + SUMO2(h) --> Sp100(h){sumo2} (sumoylation)
Sp100(h) + sumo1(h) <==> Sp100(h):sumo1(h) (binding)
Sp100(h) --> Sp100(h) (expression).
Sp100(h) --> Sp100(h) (translocation)
IFNalpha2b(h) --> Sp100(h) (increase of abundance)
Sp100(h) --> Sp100-HMG(h) (expression).
Sp100-A(h) + c-Ets-1(h) <==> Sp100-A(h):c-Ets-1(h) (binding)
Sp100(h) --> Sp100-A(h) (expression).
Sp100(h) --> Sp100-B(h) (expression).
Sp100(h) --> Sp100-C(h) (expression).
SpAlt-C(h) + sumo1(h) --> SpAlt-C(h){sumo} (sumoylation)
Sp100(h) --> SpAlt-C(h) (expression).

Location (AA)	PTM type	Literature	Database
Post Transcriptional Modification [Top]
18	Phosphoserine.		Swiss-Prot 53.0
157	Phosphoserine.		Swiss-Prot 53.0
327	Phosphoserine.		Swiss-Prot 53.0
328	Phosphoserine.		Swiss-Prot 53.0
331	Phosphoserine.		Swiss-Prot 53.0
334	Phosphoserine.		Swiss-Prot 53.0
335	Phosphothreonine.		Swiss-Prot 53.0
407	Phosphoserine.		Swiss-Prot 53.0
409	Phosphoserine.		Swiss-Prot 53.0
410	Phosphoserine.		Swiss-Prot 53.0
451	Phosphoserine.		Swiss-Prot 53.0
452	Phosphoserine.		Swiss-Prot 53.0
453	Phosphoserine.		Swiss-Prot 53.0
456	Phosphoserine.		Swiss-Prot 53.0
459	Phosphoserine.		Swiss-Prot 53.0
297	Glycyl lysine isopeptide (Lys-Gly)(interchain with G-Cter in SUMO)(Probable).		Swiss-Prot 53.0
157	Phosphoserine	17081983	Phospho.ELM 6.0
407	Phosphoserine	17081983	Phospho.ELM 6.0
409	Phosphoserine	17081983	Phospho.ELM 6.0
410	Phosphoserine	17081983	Phospho.ELM 6.0
18	Phosphoserine	17081983	Phospho.ELM 6.0
327	Phosphoserine	17081983	Phospho.ELM 6.0
328	Phosphoserine	17081983	Phospho.ELM 6.0
331	Phosphoserine	17081983	Phospho.ELM 6.0
334	Phosphoserine	17081983	Phospho.ELM 6.0
335	Phosphothreonine	17081983	Phospho.ELM 6.0
451	Phosphoserine	17081983	Phospho.ELM 6.0
452	Phosphoserine	17081983	Phospho.ELM 6.0
453	Phosphoserine	17081983	Phospho.ELM 6.0
456	Phosphoserine	17081983	Phospho.ELM 6.0
459	Phosphoserine	17081983	Phospho.ELM 6.0