Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

688

Name

KLF5

Synonymous

BTEB2|CKLF|IKLF;Kruppel-like factor 5 (intestinal);KLF5;Kruppel-like factor 5 (intestinal)

Definition

BTE-binding protein 2|GC box binding protein 2|Klf5C isoform|Krueppel-like factor 5|basic transcription element binding protein 2|colon krueppel-like factor|colon kruppel-like factor|intestinal-enriched krueppel-like factor|intestinal-enriched kruppel-lik

Position

13q22.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

BTEB2(h) --> BIRC5(h) (DNA binding).
BTEB2(h) --> MKP-1(h) (increase of abundance)
BTEB2(h) --> ERK(h){p} (increase of phosphorylation)
BTEB2(h) --> MKP-1(h){pS359} (increase of phosphorylation)
BTEB2(h) --> c-myc(h) (DNA binding).
KLF5(h) --> BTEB2(h) (expression).
KLF5(h) --> KLF5(h) (expression).
hsa-miR-141 --/ KLF5(h) (predicted)
BTEB2(h) --> Smemb/NMHC-B(rb) (DNA binding).
BTEB2(h) --> LFER(m) (transactivation)
BTEB2(h) --> CYP1A1(r) (DNA binding).
BTEB2(h) --> GAST(h) (DNA binding).
KLF5(h) --> BTEB2(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

Methylation Profile   [Top]

Chromosome

Location

Source

chr13

Promoter: 72529643 - 72531643Agilent_014791

chr13

Promoter: 72529643 - 72531643GoldenGate_Methylation_Cancer_Panel_I

chr13

Promoter: 72529643 - 72531643GSE27584

chr13

Promoter: 72529643 - 72531643Agilent_014791_44K


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