| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 7421 |
Name | VDR |
Synonymous | NR1I1|PPP1R163;vitamin D (1,25- dihydroxyvitamin D3) receptor;VDR;vitamin D (1,25- dihydroxyvitamin D3) receptor |
Definition | 1,25-dihydroxyvitamin D3 receptor|nuclear receptor subfamily 1 group I member 1|protein phosphatase 1, regulatory subunit 163|vitamin D nuclear receptor variant 1|vitamin D3 receptor |
Position | 12q13.11 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
bag1-isoform1(h) + VDR(h) <==> bag1-isoform1(h):VDR(h) (binding) | VDR(h) --> Spp1(m) (DNA binding) | VDR(h) + RXR-alpha(h) <==> VDR(h):RXR-alpha(h) (binding) | RXR-alpha(m) + VDR(h) <==> RXR-alpha(m):VDR(h) (binding). | RXR-beta(m) + VDR(h) <==> RXR-beta(m):VDR(h) (binding). | RXR-beta(h) + VDR(h) <==> RXR-beta(h):VDR(h) (binding) | VDR(h) + RXR-beta(r) <==> VDR(h):RXR-beta(r) (binding). | VDR(h) + TRAP(h) <==> VDR(h):TRAP(h) (binding). | VDR(h) + RXR-alpha(x) <==> VDR(h):RXR-alpha(x) (binding). | SKIP(h) + VDR(h) <==> SKIP(h):VDR(h) (binding). | SRC3(h) + VDR(h) <==> SRC3(h):VDR(h) (binding) | tuberin(h) + VDR(h) <==> tuberin(h):VDR(h) (binding) | AML3(v.s.) + VDR(h) <==> AML3(v.s.):VDR(h) (binding) | AML3(r) + VDR(h) <==> AML3(r):VDR(h) (binding) | Src(h) + VDR(h) <==> Src(h):VDR(h) (binding) | TFIIB(h) + VDR(h) <==> TFIIB(h):VDR(h) (binding) | VDR(h) --> BGLAP(h) (DNA binding). | HR(r) + VDR(h) <==> HR(r):VDR(h) (binding) | VDR(h) --> CYP24A1(h) (transactivation) | TIF1a-short(h) + VDR(h) <==> TIF1a-short(h):VDR(h) (binding) | VDR(h) + SRC3-xbb2(h) <==> VDR(h):SRC3-xbb2(h) (binding) | VDR(h) --> CYP3A4(h) (DNA binding). | VDR(h) --> CYP3A7(h) (DNA binding). | VDR(h) --> PLCG1(h) (DNA binding). | calcitriol + VDR(h) <==> calcitriol:VDR(h) (binding) | lithocholate + VDR(h) <==> lithocholate:VDR(h) (binding) | 3-keto-LCA + VDR(h) <==> 3-keto-LCA:VDR(h) (binding) | VDR(h) + RXR-alpha(h) <==> VDR(h):RXR-alpha(h) (binding) | VDR(h) + TFIIB(m.s.) <==> VDR(h):TFIIB(m.s.) (binding) | VDR(h) + ATP --PKCbeta(m)--> VDR(h){pS51} + ADP (phosphorylation) | VDR(h) + ATP --> VDR(h){p} + ADP (phosphorylation) | VDR(h) + ATP --CKII-alpha(h)--> VDR(h){pS208} + ADP (phosphorylation) | VDR(h) + TFIIB(h) <==> VDR(h):TFIIB(h) (binding) | VDR(h) --> Bglap(r) (transactivation) | VDR(h) + SRC-1(h) <==> VDR(h):SRC-1(h) (binding) | VDR(h) + CBP(m.s.) <==> VDR(h):CBP(m.s.) (binding) | VDR(h) + SRC-1(r) <==> VDR(h):SRC-1(r) (binding) | VDR(h) + RXR-alpha(r) <==> VDR(h):RXR-alpha(r) (binding) | VDR(h) + DRIP205(r) <==> VDR(h):DRIP205(r) (binding) | VDR(h) + TIF2(m) <==> VDR(h):TIF2(m) (binding) | IGFBP-5(h) + VDR(h) <==> IGFBP-5(h):VDR(h) (binding) | IGFBP-3(h) + VDR(h) <==> IGFBP-3(h):VDR(h) (binding) | VDR(h) + HR(h) <==> VDR(h):HR(h) (binding) | PLZF(h) + VDR(h) <==> VDR(h):PLZF(h) (binding) | VDR(h) + PLZF(h) <==> VDR(h):PLZF(h) (binding) | Pit-1(h) + VDR(h) <==> Pit-1(h):VDR(h) (binding) | VDR(h) + TRIP7(h) <==> VDR(h):TRIP7(h) (binding) | VDR(h) + RIP140(h) <==> VDR(h):RIP140(h) (binding) | VDR(h) + SHP(h) <==> VDR(h):SHP(h) (binding) | VDR(h) + SWAP2(h) <==> VDR(h):SWAP2(h) (binding) | VDR(h) + GATE-16(h) <==> VDR(h):GATE-16(h) (binding) | VDR(h) + GEC-1(h) <==> VDR(h):GEC-1(h) (binding) | VDR(h) + dihydroxyacetone phosphate acyltransferase(h) <==> VDR(h):dihydroxyacetone phosphate acyltransferase(h) (binding) | VDR(h) + H63(h) <==> VDR(h):H63(h) (binding) | VDR(h) + S8(h) <==> VDR(h):S8(h) (binding) | VDR(h) + RXR-gamma(h) <==> VDR(h):RXR-gamma(h) (binding) | VDR(h) --> ABCB1(h) (DNA binding; transactivation). | VDR(h) --/ Ibsp(r) (transrepression) | VDR(h) --> VDR(h) (expression). | TFIIB(h) --> VDR(h) (binding) | RXR-alpha(h) --> VDR(h) (binding) | CaSR(h) --> VDR(h) (increase of abundance) | p38alpha(h) --> VDR(h) (increase of abundance) | VDR(h) --> BGLAP(h) (DNA binding; transregulation). | VDR(h) --> Bglap(r) (DNA binding). | VDR(h) --> Calb1(m) (DNA binding; transregulation). | VDR(h) --> PTH(c) (DNA binding; transregulation). | VDR(h) --> PTHR1(r) (DNA binding). | VDR(h) --> CAII(c) (DNA binding; transregulation). | VDR(h) --> CDKN1A(h) (DNA binding; transregulation). | VDR(h) --> ITGB3(c) (DNA binding). | VDR(h) --> Fos(m) (DNA binding). | VDR(h) --> S100G(h) (DNA binding). | VDR(h) --/ GH1(h) (DNA binding; transrepression). | VDR(h) + Pit-1B(r) <==> VDR(h):Pit-1B(r) (binding) [re | VDR(h) + NCOR1-isoform1(m) <==> VDR(h):NCOR1-isoform1(m) (binding) | VDR(h) + SRC-1(h) <==> VDR(h):SRC-1(h) (binding) | VDR(h) + PGC-1(h) <==> VDR(h):PGC-1(h) (binding) | VDR(h) + SMRT(m.s.) <==> VDR(h):SMRT(m.s.) (binding) | VDR(h) + NCOR1(m) <==> VDR(h):NCOR1(m) (binding) | VDR(h) + RXR-alpha(m.s.) <==> VDR(h):RXR-alpha(m.s.) (binding) | VDR(h) + NCOR1(m.s.) <==> VDR(h):NCOR1(m.s.) (binding) | VDR(h) + PLZF(m.s.) <==> VDR(h):PLZF(m.s.) (binding) | VDR(h) + PML-3(m.s.) <==> VDR(h):PML-3(m.s.) (binding) | VDR(h) + MTG8(m.s.) <==> VDR(h):MTG8(m.s.) (binding) | VDR(h) + AML1(m.s.) <==> VDR(h):AML1(m.s.) (binding) | VDR(h) + SKIP(h) <==> VDR(h):SKIP(h) (binding) | VDR(h) + RXR(m.s.) <==> VDR(h):RXR(m.s.) (binding) | MO15(h) + VDR(h) <==> MO15(h):VDR(h) (binding) | VDR(h) + TFIIB(h) <==> VDR(h):TFIIB(h) (binding) | SRC-1(m.s.) + VDR(h) <==> SRC-1(m.s.):VDR(h) (binding) | ASC-2(r) + VDR(h) <==> ASC-2(r):VDR(h) (binding) | ASC-2(h) + VDR(h) <==> ASC-2(h):VDR(h) (binding) | VDR(h) + cyclinD3(h) <==> VDR(h):cyclinD3(h) (binding) | VDR(h) + cyclinD3(m) <==> VDR(h):cyclinD3(m) (binding) | VDR(h) --> Bglap(r) (transactivation) | VDR(h) + DRIP205-isoform1(h) <==> VDR(h):DRIP205-isoform1(h) (binding) | RXR-alpha(h) + VDR(h) <==> RXR-alpha(h):VDR(h) (binding) | VDR(h) --> Vdr(m) (DNA binding; transactivation). | VDR(h) + Rbp2(h) <==> VDR(h):Rbp2(h) (binding) | POU2F1(m.s.) + VDR(h) <==> POU2F1(m.s.):VDR(h) (binding) | Oct-2(m.s.) + VDR(h) <==> Oct-2(m.s.):VDR(h) (binding) | VDR(h) --> Spp1(m) (DNA binding). | VDR(h) --> Cyp24a1(r) (DNA binding; transactivation). | lithocholate + VDR(h) <==> lithocholate:VDR(h) (binding) | 3-keto-LCA + VDR(h) <==> 3-keto-LCA:VDR(h) (binding) | FXR(m.s.) + VDR(h) <==> FXR(m.s.):VDR(h) (binding) | SRC-1(m) + VDR(h) <==> SRC-1(m):VDR(h) (binding) | VDR(h) + TFIIB(m.s.) <==> VDR(h):TFIIB(m.s.) (binding) | calcitriol + VDR(h) <==> calcitriol:VDR(h) (binding) | VDR(h) + ATP --CKII-alpha(b):CKII-alpha2(b):(CKII-beta(b))2--> VDR(h){pS208} + ADP (phosphorylation) | VDR(h) + ATP --> VDR(h){pS208} + ADP (phosphorylation) | VDR(h) --/ BGLAP(h) (transrepression) | VDR(h) + Alien(h) <==> VDR(h):Alien(h) (binding) | VDR(h) --/ NPPA(h) (transrepression) | VDR(h) + TIF2(m) <==> VDR(h):TIF2(m) (binding) | VDR(h) + SRC3-xbb2(h) <==> VDR(h):SRC3-xbb2(h) (binding) | VDR(h) --> BGLAP(h) (transactivation) | VDR(h) + Hsp70(b) <==> VDR(h):Hsp70(b) (binding) | TAF2(h) + VDR(h) <==> TAF2(h):VDR(h) (binding) | VDR(h) + RXR-alpha(m) <==> VDR(h):RXR-alpha(m) (binding) | DRIP205(m.s.) + VDR(h) <==> DRIP205(m.s.):VDR(h) (binding) | VDR(h) + SKIP(m.s.) <==> VDR(h):SKIP(m.s.) (binding) | VDR(h) + Grip1(m) <==> VDR(h):Grip1(m) (binding) | SKIP(m.s.) + Grip1(m) + VDR(h) <==> SKIP(m.s.):VDR(h):Grip1(m) (binding) | DRIP(h) + VDR(h) <==> DRIP(h):VDR(h) (binding) | DRIP100(h) + VDR(h) <==> DRIP100(h):VDR(h) (binding) | RXR-beta(h) + VDR(h) <==> RXR-beta(h):VDR(h) (binding) | GRIP1(m.s.) + VDR(h) <==> GRIP1(m.s.):VDR(h) (binding) | CREB1(m.s.) + VDR(h) <==> CREB1(m.s.):VDR(h) (binding) | VDR(h) --> CYP24A1(h) (transactivation) | VDR(h) + beta-catenin(m.s.) <==> VDR(h):beta-catenin(m.s.) (binding) | VDR(h) --> POU1F1(h) (DNA binding). | VDR(h) --> IL12B(h) (transactivation) | VDR(h) --> EGFR(h) (DNA binding). | VDR(h) --> VDR(h) (expression). | VDR(h):Alien(h) <==> VDR(h) + Alien(h) (dissociation) | VDR(h):NCOR1-isoform1(m) <==> VDR(h) + NCOR1-isoform1(m) (dissociation) | VDR-M4(h) + TFIIB(h) <==> VDR-M4(h):TFIIB(h) (binding) | VDR(h) --> VDR-M4(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
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Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
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chr12 |
Promoter: 46584581 - 46586581 | Agilent_014791 |
chr12 |
Promoter: 46584581 - 46586581 | GSE27584 |
chr12 |
Promoter: 46584581 - 46586581 | GSE27584 |
chr12 |
Promoter: 46584581 - 46586581 | Agilent_014791_44K |
chr12 |
Promoter: 46584581 - 46586581 | PMID:12796396 |
chr12 |
Promoter: 46584581 - 46586581 | PMID:12796396 |