| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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|---|---|
Gene ID | 7431 |
Name | VIM |
Synonymous | CTRCT30|HEL113;vimentin;VIM;vimentin |
Definition | epididymis luminal protein 113 |
Position | 10p13 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
vimentin(h) --Caspase-3(h)--> protein remnants (processing) | vimentin(h) + calpain-1(h) <==> vimentin(h):calpain-1(h) (binding) | vimentin(h) + ATP --Aurora-B(r)--> vimentin(h){pS72} + ADP (phosphorylation) | Mi2-alpha(h) + vimentin(h) <==> Mi2-alpha(h):vimentin(h) (binding) | zhx1(h) + vimentin(h) <==> zhx1(h):vimentin(h) (binding) | NFL(h) + vimentin(h) <==> NFL(h):vimentin(h) (binding) | vimentin(h) + vimentin(h) <==> vimentin(h):vimentin(h) (oligomerization) | vimentin(h) + MGMT(h) <==> vimentin(h):MGMT(h) (binding) | beta2-spectrin(h) + lamin B(h) + actin(h) + vimentin(h) + plectin(h) <==> beta2-spectrin(h):lamin B(h):actin(h):vimentin(h):plectin(h) (binding) | vimentin(h) + lamin B(h) <==> vimentin(h):lamin B(h) (binding) | plectin(h) + moesin(h) + beta2-spectrin(h) + actin(h) + vimentin(h) <==> plectin(h):moesin(h):beta2-spectrin(h):actin(h):vimentin(h) (binding) | vimentin(h) + actin(h) + beta2-spectrin(h) + plectin(h) <==> vimentin(h):actin(h):beta2-spectrin(h):plectin(h) (binding) | actin(h) + vimentin(h) + plakoglobin(h) + beta-catenin(h) + alpha-catenin(h) + VE-cadherin(h) <==> actin(h):vimentin(h):plakoglobin(h):beta-catenin(h):alpha-catenin(h):VE-cadherin(h) (binding) | vimentin(h) + VE-cadherin(h) <==> vimentin(h):VE-cadherin(h) (binding) | torsin-1(h) + LAP1B(h) + KNS2(h) + alpha-tubulin(h) + actin(h) + vimentin(h) <==> torsin-1(h):vimentin(h):KNS2(h):alpha-tubulin(h):actin(h):LAP1B(h) (binding) | beta-catenin(h) + plakoglobin(h) + vimentin(h) + VE-cadherin(h) <==> beta-catenin(h):plakoglobin(h):vimentin(h):VE-cadherin(h) (binding) | CIZ(h) + vimentin(h) <==> CIZ(h):vimentin(h) (binding) | Beta-4A(h) + vimentin(h) <==> Beta-4A(h):vimentin(h) (binding) | vimentin(h) + ATP --Cdk1(h)--> vimentin(h){pS55} + ADP (phosphorylation) | vimentin(h) + ATP --ROCKs(h)--> vimentin(h){pS71} + ADP (phosphorylation) | vimentin(h) + ATP --Aurora-B(h)--> vimentin(h){pS72} + ADP (phosphorylation) | 14-3-3gamma(h) + vimentin(h) <==> 14-3-3gamma(h):vimentin(h) (binding) | TRIM29(m.s.) + vimentin(h) <==> TRIM29(m.s.):vimentin(h) (binding) | GFAP(h) + vimentin(h) <==> GFAP(h):vimentin(h) (binding) | ablim1(h) + vimentin(h) <==> ablim1(h):vimentin(h) (binding) | PSMA1(h) + vimentin(h) <==> PSMA1(h):vimentin(h) (binding) | vimentin(h) + elfin(h) <==> vimentin(h):elfin(h) (binding) | vimentin(h) + FLJ43995(h) <==> vimentin(h):FLJ43995(h) (binding) | vimentin(h) + MYST2(h) <==> vimentin(h):MYST2(h) (binding) | vimentin(h) + DRR1(h) <==> vimentin(h):DRR1(h) (binding) | vimentin(h) + ribc2(h) <==> vimentin(h):ribc2(h) (binding) | vimentin(h) + GCP-4(h) <==> vimentin(h):GCP-4(h) (binding) | vimentin(h) + APIP2(h) <==> vimentin(h):APIP2(h) (binding) | vimentin(h) + Keratin-20(h) <==> vimentin(h):Keratin-20(h) (binding) | vimentin(h) + PIST(h) <==> vimentin(h):PIST(h) (binding) | vimentin(h) + ALS2CR1(h) <==> vimentin(h):ALS2CR1(h) (binding) | vimentin(h) + NOC4(h) <==> vimentin(h):NOC4(h) (binding) | vimentin(h) + tchp(h) <==> vimentin(h):tchp(h) (binding) | vimentin(h) + als2cr11(h) <==> vimentin(h):als2cr11(h) (binding) | S8(h) + vimentin(h) <==> S8(h):vimentin(h) (binding) | atrophin-1(h) + vimentin(h) <==> atrophin-1(h):vimentin(h) (binding) | ANT3(h) + vimentin(h) <==> ANT3(h):vimentin(h) (binding) | FBP(h) + vimentin(h) <==> FBP(h):vimentin(h) (binding) | SIAHBP1(h) + vimentin(h) <==> SIAHBP1(h):vimentin(h) (binding) | Caspase-8(h) + vimentin(h) <==> Caspase-8(h):vimentin(h) (binding) | CREB1(h) + vimentin(h) <==> CREB1(h):vimentin(h) (binding) | man2a2(h) + vimentin(h) <==> man2a2(h):vimentin(h) (binding) | Rad51(h) + vimentin(h) <==> Rad51(h):vimentin(h) (binding) | sumo3(h) + vimentin(h) <==> sumo3(h):vimentin(h) (binding) | SUMO2(h) + vimentin(h) <==> SUMO2(h):vimentin(h) (binding) | TBPA(h) + vimentin(h) <==> TBPA(h):vimentin(h) (binding) | DEC1(h) + vimentin(h) <==> DEC1(h):vimentin(h) (binding) | BRAF35(h) + vimentin(h) <==> BRAF35(h):vimentin(h) (binding) | PRAF1(h) + vimentin(h) <==> PRAF1(h):vimentin(h) (binding) | PAIRBP1(h) + vimentin(h) <==> PAIRBP1(h):vimentin(h) (binding) | SIR2L6(h) + vimentin(h) <==> SIR2L6(h):vimentin(h) (binding) | ARS2(h) + vimentin(h) <==> ARS2(h):vimentin(h) (binding) | crct1(h) + vimentin(h) <==> crct1(h):vimentin(h) (binding) | kif15(h) + vimentin(h) <==> kif15(h):vimentin(h) (binding) | L44mt(h) + vimentin(h) <==> L44mt(h):vimentin(h) (binding) | vimentin(h) + RIF1(h) <==> vimentin(h):RIF1(h) (binding) | VIM(h) --> vimentin(h) (expression). | EGF(m.s.) --> vimentin(h) (increase of abundance) | CHIP(h) --/ vimentin(h) (decrease of abundance) | vimentin(h) + MYST2(h) <==> vimentin(h):MYST2(h) (binding) | Mi2-alpha(h) + vimentin(h) <==> Mi2-alpha(h):vimentin(h) (binding) | vimentin(h) + PIASy(h) <==> vimentin(h):PIASy(h) (binding) | vimentin(h) + ESET(h) <==> vimentin(h):ESET(h) (binding) | vimentin(h) + NFL(h) <==> vimentin(h):NFL(h) (binding) | vimentin(h) + endophilin 3(h) <==> vimentin(h):endophilin 3(h) (binding) | vimentin(h) + vimentin(h) <==> vimentin(h):vimentin(h) (oligomerization) | vimentin(h) + ALEX2(h) <==> vimentin(h):ALEX2(h) (binding) | vimentin(h) + CRMP1(h) <==> vimentin(h):CRMP1(h) (binding) | vimentin(h) + COPS6(h) <==> vimentin(h):COPS6(h) (binding) | vimentin(h) + Periphilin-1(h) <==> vimentin(h):Periphilin-1(h) (binding) | vimentin(h) + CRMP1(h) <==> vimentin(h):CRMP1(h) (binding) | vimentin(h) + menin(m.s.) <==> vimentin(h):menin(m.s.) (binding) | Periplakin(h) + vimentin(h) <==> Periplakin(h):vimentin(h) (binding) | DMN(h) + vimentin(h) <==> DMN(h):vimentin(h) (binding) | vimentin(h) + CIZ(h) <==> vimentin(h):CIZ(h) (binding) | VIM(h) --> vimentin(h) (expression). |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
2 | N-acetylserine. | Swiss-Prot 53.0 | 5 | Phosphoserine. | Swiss-Prot 53.0 | 7 | Phosphoserine (by PKA and PKC). | Swiss-Prot 53.0 | 8 | Phosphoserine. | Swiss-Prot 53.0 | 9 | Phosphoserine (by PKC). | Swiss-Prot 53.0 | 10 | Phosphoserine (by PKC). | Swiss-Prot 53.0 | 25 | Phosphoserine (by PKA and PKC) (Bysimilarity). | Swiss-Prot 53.0 | 26 | Phosphoserine (by PKC) (By similarity). | Swiss-Prot 53.0 | 27 | Phosphoserine. | Swiss-Prot 53.0 | 34 | Phosphoserine (by PKC) (By similarity). | Swiss-Prot 53.0 | 39 | Phosphoserine (by CaMK2, PKA and PKC). | Swiss-Prot 53.0 | 42 | Phosphoserine (by PKC). | Swiss-Prot 53.0 | 47 | Phosphoserine (by PKA) (By similarity). | Swiss-Prot 53.0 | 51 | Phosphoserine (by PKA and PKC) (Bysimilarity). | Swiss-Prot 53.0 | 56 | Phosphoserine. | Swiss-Prot 53.0 | 66 | Phosphoserine (by PKA and PKC) (Bysimilarity). | Swiss-Prot 53.0 | 72 | Phosphoserine. | Swiss-Prot 53.0 | 73 | Phosphoserine. | Swiss-Prot 53.0 | 83 | Phosphoserine (by CaMK2) (By similarity). | Swiss-Prot 53.0 | 117 | Phosphotyrosine. | Swiss-Prot 53.0 | 214 | Phosphoserine. | Swiss-Prot 53.0 | 412 | Phosphoserine. | Swiss-Prot 53.0 | 420 | Phosphoserine. | Swiss-Prot 53.0 | 430 | Phosphoserine. | Swiss-Prot 53.0 | 458 | Phosphothreonine. | Swiss-Prot 53.0 | 459 | Phosphoserine. | Swiss-Prot 53.0 | 38 | Phosphoserine (MAPKAPK2;PAK) | 11895474;12761892 | Phospho.ELM 6.0 | 50 | Phosphoserine (MAPKAPK2;PAK) | 11895474;12761892;15713670 | Phospho.ELM 6.0 | 55 | Phosphoserine (MAPKAPK2;CDK) | 7983050;12761892;15713670;15766329;17081983 | Phospho.ELM 6.0 | 82 | Phosphoserine (MAPKAPK2;CaM) | 12761892;9794428;16140754 | Phospho.ELM 6.0 | 60 | Phosphotyrosine | 15592455 | Phospho.ELM 6.0 | 425 | Phosphothreonine | 15274135 | Phospho.ELM 6.0 | 52 | Phosphotyrosine | 16497976 | Phospho.ELM 6.0 | 26 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 213 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 411 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 429 | Phosphoserine | 17081983 | Phospho.ELM 6.0 | 458 | Phosphoserine | 17081983 | Phospho.ELM 6.0 |
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Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
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chr10 |
Promoter: 17309804 - 17311804 | Agilent_014791 |
chr10 |
Promoter: 17309804 - 17311804 | GoldenGate_Methylation_Cancer_Panel_I |
chr10 |
Promoter: 17309804 - 17311804 | GSE27584 |
chr10 |
Promoter: 17309804 - 17311804 | Agilent_014791_44K |
chr10 |
Promoter: 17309804 - 17311804 | PMID:16077070 |