Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7980

Name

TFPI2

Synonymous

PP5|REF1|TFPI-2;tissue factor pathway inhibitor 2;TFPI2;tissue factor pathway inhibitor 2

Definition

placental protein 5|retinal pigment epithelium cell factor 1

Position

7q22

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

ADAMTS-1(h) + TFPI2(h) <==> ADAMTS-1(h):TFPI2(h) (binding)
TFPI2(h) --ADAMTS-1(h)--> TFPI2-p6(h) + protein remnants (cleavage)
TFPI2(h) --> TFPI2(h) (expression).
ADAMTS-1(h) + TFPI2(h) <==> ADAMTS-1(h):TFPI2(h) (binding)
TFPI2(h) --> TFPI2(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

116N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0
170N-linked (GlcNAc...) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr7

Promoter: 93357501 - 93359501Agilent_014791

chr7

Promoter: 93357501 - 93359501GoldenGate_Methylation_Cancer_Panel_I

chr7

Promoter: 93357501 - 93359501GSE27584

chr7

Promoter: 93357501 - 93359501Agilent_014791_44K

chr7

Promoter: 93357501 - 93359501PMID:15592528

chr7

Promoter: 93357501 - 93359501PMID:16424060

chr7

Promoter: 93357501 - 93359501PMID:16965396

chr7

Promoter: 93357501 - 93359501PMID:12881707

chr7

Promoter: 93357501 - 93359501PMID:15685245


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