Entrez Gene

Basic Information
Gene ID	8567
Name	MADD
Synonymous	DENN\|IG20\|RAB3GEP;MAP-kinase activating death domain;MADD;MAP-kinase activating death domain
Definition	MAP kinase-activating death domain protein\|Rab3 GDP/GTP exchange factor\|differentially expressed in normal and neoplastic cells\|insulinoma glucagonoma clone 20
Position	11p11.2
Gene Type	protein-coding
Gene Regulation:	Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase [Top]

Regulation From TransFac database
Transcription Factors [Top]
TNFR1(h) + MADD(h) <==> TNFR1(h):MADD(h) (binding)
Vps13D(h) + MADD(h) <==> Vps13D(h):MADD(h) (binding)
MADD(h) --> MADD(h) (expression).
MADDa(h) + ATP --JNK3(r)--> MADDa(h){p} + ADP (phosphorylation)
MADD(h) --> MADDa(h) (expression).
MADD(h) --> MADD-xbb2(h) (expression).

Location (AA)	PTM type	Database
Post Transcriptional Modification [Top]
1059	Phosphoserine (By similarity).	Swiss-Prot 53.0
1061	Phosphothreonine (By similarity).	Swiss-Prot 53.0