Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

8682

Name

PEA15

Synonymous

HMAT1|HUMMAT1H|MAT1|MAT1H|PEA-15|PED;phosphoprotein enriched in astrocytes 15;PEA15;phosphoprotein enriched in astrocytes 15

Definition

15 kDa phosphoprotein enriched in astrocytes|astrocytic phosphoprotein PEA-15|homolog of mouse MAT-1 oncogene|mammary transforming gene 1, mouse, homolog of|phosphoprotein enriched in diabetes

Position

1q21.1

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

Omi(h) + PEA15(h) <==> Omi(h):PEA15(h) (binding)
PEA15(h) + Omi(m.s.) <==> PEA15(h):Omi(m.s.) (binding)
PEA15(h) --> ERK1(ha){p} (increase of phosphorylation)
PEA15(h) --> ERK2(ha){p} (increase of phosphorylation)
PEA15(h) --> PEA15(h) (expression).
IGF-1(m.s.) --> PEA15(h) (increase of abundance)
PEA15(h) + Omi(h) <==> PEA15(h):Omi(h) (binding)
PEA15(h) --> protein remnants (cleavage)
PEA15(h) --Omi(m.s.)--> protein remnants (cleavage)
PEA15(h) + pld1(h) <==> PEA15(h):pld1(h) (binding)
PEA15(h) --> PEA15(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

104Phosphoserine.Swiss-Prot 53.0
116Phosphoserine.Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr1

Promoter: 158440251 - 158442251GSE27584

chr1

Promoter: 158440251 - 158442251Agilent_014791_44K

chr1

Promoter: 158440251 - 158442251E-GEOD-20553


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