| General information | Literature | Expression | Regulation | Variant | Interaction |
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Basic Information |
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Gene ID | 8856 |
Name | NR1I2 |
Synonymous | BXR|ONR1|PAR|PAR1|PAR2|PARq|PRR|PXR|SAR|SXR;nuclear receptor subfamily 1, group I, member 2;NR1I2;nuclear receptor subfamily 1, group I, member 2 |
Definition | nuclear receptor subfamily 1 group I member 2|orphan nuclear receptor PAR1|orphan nuclear receptor PXR|pregnane X nuclear receptor variant 2|pregnane X receptor|steroid and xenobiotic receptor |
Position | 3q12-q13.3 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
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Transcription Factors [Top] |
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Regulation From TransFac database |
SXR(h) --> MMTV(MMTV) (DNA binding). | NR1I2(h) --> SXR(h) (expression). | PXR-isoform1A(h) --> UGT1A(h) (DNA binding; transactivation). | SMRT(h) + PXR-isoform1A(h) <==> SMRT(h):PXR-isoform1A(h) (binding) | SRC3(m.s.) + PXR-isoform1A(h) <==> SRC3(m.s.):PXR-isoform1A(h) (binding) | PXR-isoform1A(h) --> CYP3A4(h) (transactivation) | NR1I2(h) --> PXR-isoform1A(h) (expression). | NR1I2(h) --> PXR-isoform3(h) (expression). | Pit-1B(r) + PXR(h) <==> Pit-1B(r):PXR(h) (binding) | PXR(h) + SRC-1(h) <==> PXR(h):SRC-1(h) (binding) | PXR(h) + NCOR1-isoform1(m) <==> PXR(h):NCOR1-isoform1(m) (binding) | PXR(h) --> CYP3A4(h) (DNA binding). | lithocholate + PXR(h) <==> lithocholate:PXR(h) (binding) | 3-keto-LCA + PXR(h) <==> 3-keto-LCA:PXR(h) (binding) | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane + PXR(h) <==> 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestane:PXR(h) (binding) | cholestane-3,7,12,25-tetrol + PXR(h) <==> cholestane-3,7,12,25-tetrol:PXR(h) (binding) | PXR(h) + PGC-1(h) <==> PXR(h):PGC-1(h) (binding) | PXR(h) + NEFA(h) <==> PXR(h):NEFA(h) (binding) | PXR(h) + alpha-actinin-2(h) <==> PXR(h):alpha-actinin-2(h) (binding) | PXR(h) + S8(h) <==> PXR(h):S8(h) (binding) | PXR(h) + RXR-gamma(h) <==> PXR(h):RXR-gamma(h) (binding) | PXR(h) + RXR-beta(h) <==> PXR(h):RXR-beta(h) (binding) | PXR(h) + RXR-alpha(h) <==> PXR(h):RXR-alpha(h) (binding) | NR1I2(h) --> PXR(h) (expression). | NR1I2(h) --> PXR-isoform1B(h) (expression). | NR1I2(h) --> PXR-isoform1C(h) (expression). | NR1I2(h) --> PXR-isoform2A(h) (expression). | NR1I2(h) --> PXR-isoform2B(h) (expression). | NR1I2(h) --> PXR-isoform2C(h) (expression). | NR1I2(h) --> PXR(h) (expression). | hsa-miR-148a --/ PXR(h) (translational repression). |
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Post Transcriptional Modification [Top] | |||
There is no record for NR1I2 | |||
Methylation Profile [Top] | ||
There is no record for NR1I2 | ||