| General information | Literature | Expression | Regulation | Variant | Interaction |
Basic Information | |
|---|---|
Gene ID | 9365 |
Name | KL |
Synonymous | -;klotho;KL;klotho |
Definition | - |
Position | 13q12 |
Gene Type | protein-coding |
Gene Regulation: | Upstream microRNAs Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
Experimentally verified miRNA from miRTarBase [Top] | |||
![]() |
Transcription Factors [Top] |
Regulation From TransFac database | KL(h) --> klotho isoform-membrane-bound(h) (expression). | klotho(h) --> ERK1(h){p} (increase of phosphorylation) | klotho(h) --> ERK2(h){p} (increase of phosphorylation) | KL(h) --> klotho(h) (expression). | KL(h) --> klotho isoform-secreted(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
Location (AA) | PTM type | Literature | Database | 106 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 159 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 283 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 344 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 497 | Phosphotyrosine (By similarity). | Swiss-Prot 53.0 | 607 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 612 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 694 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
Chromosome | Location | Source |
|---|---|---|
chr13 |
Promoter: 32487071 - 32489071 | Agilent_014791 |
chr13 |
Promoter: 32487071 - 32489071 | GSE27584 |
chr13 |
Promoter: 32487071 - 32489071 | Agilent_014791_44K |