Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

9788

Name

MTSS1

Synonymous

MIM|MIMA|MIMB;metastasis suppressor 1;MTSS1;metastasis suppressor 1

Definition

metastasis suppressor YGL-1|metastasis suppressor protein 1|missing in metastasis protein

Position

8p22

Gene Type

protein-coding

Gene Regulation:

Upstream microRNAs
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

Experimentally verified miRNA from miRTarBase   [Top]

Experimentally validated miRNA-TS gene regulation information.

Transcription Factors   [Top]

Regulation From TransFac database

GLI(m.s.) + MIM/BEG4(h) --> Krt17(m) (transactivation)
Gli2(m.s.) + MIM/BEG4(h) --> Krt17(m) (transactivation)
Gli2(m.s.) + MIM/BEG4(h) --> HNF-3beta(m) (transactivation)
MTSS1(h) --> MIM/BEG4(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

258Phosphothreonine (By similarity).Swiss-Prot 53.0
272Phosphoserine (By similarity).Swiss-Prot 53.0
315Phosphoserine (By similarity).Swiss-Prot 53.0
316Phosphoserine (By similarity).Swiss-Prot 53.0
569Phosphoserine (By similarity).Swiss-Prot 53.0

Methylation Profile   [Top]

Chromosome

Location

Source

chr8

Promoter: 125809340 - 125811340Agilent_014791

chr8

Promoter: 125809340 - 125811340GSE27584

chr8

Promoter: 125809340 - 125811340Agilent_014791_44K

chr8

Promoter: 125809340 - 125811340PMID:16367923


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