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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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Gene ID | 1002 |
Name | CDH4 |
Synonym | CAD4|RCAD;cadherin 4, type 1, R-cadherin (retinal);CDH4;cadherin 4, type 1, R-cadherin (retinal) |
Definition | R-CAD|R-cadherin|cadherin 4, type 1, preproprotein|cadherin-4|retinal cadherin |
Position | 20q13.3 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
potential | CDH4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma. |
potential | CDH4 may act as a tumor suppressor gene in human gastrointestinal tumors and can potentially be used as an early diagnostic marker for gastrointestinal tumorigenesis. |
| More detail of all 2 literatures about CDH4 | |
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Pathways and Diseases |
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Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | Cell adhesion molecules (CAMs);KEGG PATHWAY;hsa04514 |
Pathway | Myogenesis;Reactome;REACT:21303 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Cadherin signaling pathway;PANTHER;P00012 |
Disease | Volumetric brain MRI;GAD |
Disease | Volumetric brain MRI;NHGRI |
Disease | NEUROLOGICAL;GAD |
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External Links |
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Links to Entrez Gene | 1002 |
Links to all GeneRIF Items | 1002 |
Links to iHOP | 1002 |
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Sequence Information |
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Nucleotide Sequence |
>1002 : length: 2751 atgaccgcgggcgccggcgtgctccttctgctgctctcgctctccggcgcgctccgggcc cataatgaggatcttacaactagagagacctgcaaggctgggttctctgaagatgattac acggcattaatctcccaaaatattctagaaggggaaaagctacttcaagtcaagttcagc agctgtgtggggaccaaggggacacaatatgagaccaacagcatggacttcaaagttggg gcagatgggacagtcttcgccacccgggagctgcaggtcccctccgagcaggtggcgttc acggtgactgcatgggacagccagacagcagagaaatgggacgccgtggtgcggttgctg gtggcccagacctcgtccccgcactctggacacaagccgcagaaaggaaagaaggtcgtg gctctggacccctctccgcctccgaaggacaccctgctgccgtggccccagcaccagaac gccaacgggctgaggcggcgcaaacgggactgggtcatcccgcccatcaacgtgcccgag aactcgcgcgggcccttcccgcagcagctcgtgaggatccggtccgacaaagacaatgac atccccatccggtacagcatcacgggagtgggcgccgaccagccccccatggaggtcttc agcattgactccatgtccggccggatgtacgtcacaaggcccatggaccgggaggagcac gcctcttaccacctccgagcccacgctgtggacatgaatggcaacaaggtggagaacccc atcgacctgtacatctacgtcatcgacatgaatgacaaccgccctgagttcatcaaccag gtctacaacggctccgtggacgagggctccaagccaggcacctacgtgatgaccgtcacg gccaacgatgctgacgacagcaccacggccaacgggatggtgcggtaccggatcgtgacc cagaccccacagagcccgtcccagaatatgttcaccatcaacagcgagactggagatatc gtcacagtggcggctggcctggaccgagagaaagttcagcagtacacagtcatcgttcag gccacagatatggaaggaaatctcaactatggcctctcaaacacagccacagccatcatc acggtgacagatgtgaatgacaacccgccagaatttaccgccagcacgtttgcaggggag gtccccgaaaaccgcgtggagaccgtggtcgcaaacctcacggtgatggaccgagatcag ccccactctccaaactggaatgccgtttaccgcatcatcagtggggatccatccgggcac ttcagcgtccgcacagaccccgtaaccaacgagggcatggtcaccgtggtgaaggcagtc gactacgagctcaacagagctttcatgctgacagtgatggtgtccaaccaggcgcccctg gccagcggaatccagatgtccttccagtccacggcaggggtgaccatctccatcatggac atcaacgaggctccctacttcccctcaaaccacaagctgatccgcctggaggagggcgtg ccccccggcaccgtgctgaccacgttttcagctgtggaccctgaccggttcatgcagcag gctgtgagatactcaaagctgtcagacccagcgagctggctgcacatcaatgccaccaac ggccagatcaccacggcggcagtgctggaccgtgagtccctctacaccaaaaacaacgtc tacgaggccaccttcctggcagctgacaatgggatacccccggccagcggcaccgggacc ctccagatctatctcattgacatcaacgacaacgcccctgagctgctgcccaaggaggcg cagatctgcgagaagcccaacctgaacgccatcaacatcacggcggccgacgctgacgtc gaccccaacatcggcccctacgtcttcgagctgccctttgtcccggcggccgtgcggaag aactggaccatcacccgcctgaacggtgactatgcccaactcagcttgcgcatcctgtac ctggaggccgggatgtatgacgtccccatcatcgtcacagactctggaaaccctcccctg tccaacacgtccatcatcaaagtcaaggtgtgcccatgtgatgacaacggggactgcacc accattggcgcagtggcagcggctggtctgggcaccggtgccatcgtggccatcctcatc tgcatcctcatcctgctgaccatggtcctgctgtttgtcatgtggatgaagcggcgagag aaggagcgccacacgaagcagctgctcattgaccccgaggacgacgtccgcgacaacatc ctcaagtatgacgaggaaggcggtggcgaggaggaccaggactacgacctcagccagctg cagcagccggaagccatggggcacgtgccaagcaaagcccctggcgtgcgtcgcgtggat gagcggccggtgggcgctgagccccagtacccgatcaggcccatggtgccgcacccaggc gacatcggtgacttcatcaatgagggactccgcgctgctgacaacgaccccacggcaccc ccctatgactccctgctggtcttcgactacgaggggagcggctccaccgcaggctccgtc agctccctgaactcatccagttccggggaccaagactacgattacctcaacgactggggg cccagattcaagaagctggcggacatgtatggaggtggtgaagaggattga |
Protein Sequence |
>1002 : length: 916 MTAGAGVLLLLLSLSGALRAHNEDLTTRETCKAGFSEDDYTALISQNILEGEKLLQVKFS SCVGTKGTQYETNSMDFKVGADGTVFATRELQVPSEQVAFTVTAWDSQTAEKWDAVVRLL VAQTSSPHSGHKPQKGKKVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPE NSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEH ASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVT ANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQ ATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQ PHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPL ASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQ AVRYSKLSDPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGT LQIYLIDINDNAPELLPKEAQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRK NWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCT TIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNI LKYDEEGGGEEDQDYDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQYPIRPMVPHPG DIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWG PRFKKLADMYGGGEED |