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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 1009 |
Name | CDH11 |
Synonym | CAD11|CDHOB|OB|OSF-4;cadherin 11, type 2, OB-cadherin (osteoblast);CDH11;cadherin 11, type 2, OB-cadherin (osteoblast) |
Definition | cadherin-11 |
Position | 16q21 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
reviewed | Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death. |
potential | "A 2.62 Mbp minimal region of genomic loss of chromosome 16q22 was found in retinoblastoma which contains a hotspot CDH11, implicating CDH11as a potential tumor suppressor gene in retinoblastoma." |
| More detail of all 2 literatures about CDH11 | |
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Pathways and Diseases |
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Pathway | Cell junction organization;Reactome;REACT:20676 |
Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Cadherin signaling pathway;PANTHER;P00012 |
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External Links |
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Links to Entrez Gene | 1009 |
Links to all GeneRIF Items | 1009 |
Links to iHOP | 1009 |
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Sequence Information |
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Nucleotide Sequence |
>1009 : length: 2391 atgaaggagaactactgtttacaagccgccctggtgtgcctgggcatgctgtgccacagc catgcctttgccccagagcggcgggggcacctgcggccctccttccatgggcaccatgag aagggcaaggaggggcaggtgctacagcgctccaagcgtggctgggtctggaaccagttc ttcgtgatagaggagtacaccgggcctgaccccgtgcttgtgggcaggcttcattcagat attgactctggtgatgggaacattaaatacattctctcaggggaaggagctggaaccatt tttgtgattgatgacaaatcagggaacattcatgccaccaagacgttggatcgagaagag agagcccagtacacgttgatggctcaggcggtggacagggacaccaatcggccactggag ccaccgtcggaattcattgtcaaggtccaggacattaatgacaaccctccggagttcctg cacgagacctatcatgccaacgtgcctgagaggtccaatgtgggaacgtcagtaatccag gtgacagcttcagatgcagatgaccccacttatggaaatagcgccaagttagtgtacagt atcctcgaaggacaaccctatttttcggtggaagcacagacaggtatcatcagaacagcc ctacccaacatggacagggaggccaaggaggagtaccacgtggtgatccaggccaaggac atgggtggacatatgggcggactctcagggacaaccaaagtgacgatcacactgaccgat gtcaatgacaacccaccaaagtttccgcagagcgtataccagatgtctgtgtcagaagca gccgtccctggggaggaagtaggaagagtgaaagctaaagatccagacattggagaaaat ggcttagtcacatacaatattgttgatggagatggtatggaatcgtttgaaatcacaacg gactatgaaacacaggagggggtgataaagctgaaaaagcctgtagattttgaaaccaaa agagcctatagcttgaaggtagaggcagccaacgtgcacatcgacccgaagtttatcagc aatggccctttcaaggacactgtgaccgtcaagatctcagtagaagatgctgatgagccc cctatgttcttggccccaagttacatccacgaagtccaagaaaatgcagctgctggcacc gtggttgggagagtgcatgccaaagaccctgatgctgccaacagcccgataaggtattcc atcgatcgtcacactgacctcgacagatttttcactattaatccagaggatggttttatt aaaactacaaaacctctggatagagaggaaacagcctggctcaacatcactgtctttgca gcagaaatccacaatcggcatcaggaagccaaagtcccagtggccattagggtccttgat gtcaacgataatgctcccaagtttgctgccccttatgaaggtttcatctgtgagagtgat cagaccaagccactttccaaccagccaattgttacaattagtgcagatgacaaggatgac acggccaatggaccaagatttatcttcagcctaccccctgaaatcattcacaatccaaat ttcacagtcagagacaaccgagataacacagcaggcgtgtacgcccggcgtggagggttc agtcggcagaagcaggacttgtaccttctgcccatagtgatcagcgatggcggcatcccg cccatgagtagcaccaacaccctcaccatcaaagtctgcgggtgcgacgtgaacggggca ctgctctcctgcaacgcagaggcctacattctgaacgccggcctgagcacaggcgccctg atcgccatcctcgcctgcatcgtcattctcctggtcattgtagtattgtttgtgaccctg agaaggcaaaagaaagaaccactcattgtctttgaggaagaagatgtccgtgagaacatc attacttatgatgatgaagggggtggggaagaagacacagaagcctttgatattgccacc ctccagaatcctgatggtatcaatggatttatcccccgcaaagacatcaaacctgagtat cagtacatgcctagacctgggctccggccagcgcccaacagcgtggatgtcgatgacttc atcaacacgagaatacaggaggcagacaatgaccccacggctcctccttatgactccatt caaatctacggttatgaaggcaggggctcagtggccgggtccctgagctccctagagtcg gccaccacagattcagacttggactatgattatctacagaactggggacctcgttttaag aaactagcagatttgtatggttccaaagacacttttgatgacgattcttaa |
Protein Sequence |
>1009 : length: 796 MKENYCLQAALVCLGMLCHSHAFAPERRGHLRPSFHGHHEKGKEGQVLQRSKRGWVWNQF FVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREE RAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQ VTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN GLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFIS NGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYS IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLD VNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPN FTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGA LLSCNAEAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENI ITYDDEGGGEEDTEAFDIATLQNPDGINGFIPRKDIKPEYQYMPRPGLRPAPNSVDVDDF INTRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFK KLADLYGSKDTFDDDS |