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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 10335 |
Name | MRVI1 |
Synonym | IRAG|JAW1L;murine retrovirus integration site 1 homolog;MRVI1;murine retrovirus integration site 1 homolog |
Definition | IP3R-associated cGMP kinase substrate|JAW1-related protein MRVI1|inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate|protein MRVI1 |
Position | 11p15 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | "Because other common integration sites in BXH2 leukemias encoding proto-oncogenes contain ecotropic rather than MRV viruses, it has been speculated that MRV viruses may selectively target tumor suppressor genes. ". |
| More detail of all 1 literatures about MRVI1 | |
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Pathways and Diseases |
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Pathway | Vascular smooth muscle contraction;KEGG PATHWAY;hsa04270 |
Pathway | Hemostasis;Reactome;REACT:604 |
Disease | Platelet aggregation;NHGRI |
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External Links |
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Links to Entrez Gene | 10335 |
Links to all GeneRIF Items | 10335 |
Links to iHOP | 10335 |
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Sequence Information |
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Nucleotide Sequence |
>10335 : length: 2712 atgggaatggatttgacttgtccttttggcgtctccccagcctgtggagcccaggcctct tggagcatctttggggctgacgcagcggaggttccgggcacacgtggccactcccagcag gaggctgccatgccccacattcccgaggacgaggagccccccggagagccacaggcagcc cagagccctgccggccaaggtcctcctaccgcaggagtatcttgcagtccaactcccacg attgtcctgactggggatgccacttcaccagaaggagaaaccgacaaaaacctggccaac agagttcacagtccccacaagaggctttctcaccgacacttgaaggtgtccactgcctcc ctgacatctgtggaccccgcggggcacatcattgacctggtgaatgaccagctgccagac atcagcatctcagaggaggacaagaagaaaaacctggcgctgctggaagaagccaagttg gtgagtgagcgattcctgacccgccgtgggaggaagtccaggagcagccccggagactcc ccatcagctgtttccccgaacctcagccccagcgcttctcctacatcctctcggagcaac tcacttacagtccccaccccgccaggtttggatgtgtgcagtggcccgccatcccctctg cctggagcaccaccacagaagggggatgaggccgacgtctcttcacctcaccctggcgag cctaacgtccccaaagggctagctgacaggaagcagaatgaccagaggaaagtgtctcag ggcaggctggctcctcgtcctcctccagttgagaagtccaaagagattgcaatagaacaa aaggaaaacttcgatcccctccagtaccccgagaccacacccaaaggcctagctcctgtt acaaacagcagtgggaaaatggccctgaacagccctcagcctggccccgtggagagcgag ctggggaagcagctcttgaaaacgggctgggagggcagccctctgccgagaagtccaacc caggatgcggcaggagtgggtcccccagcctcccaggggagaggcccagctggagagccg atggggcccgaggctggctccaaagctgagcttccacccactgtgtcccggcccccgctg ctgcgagggctctcctgggacagtggccctgaagaacctggcccccggctgcagaaagtg cttgccaagctgccactggcagaggaagaaaagcgttttgcaggcaaggccggcggcaag ctggccaaggcccctggtctcaaagactttcagatacaagtgcagcccgtgcggatgcag aaactgaccaagctccgagaggagcacatcctgatgagaaatcagaacttagtggggctc aagcttccagaccttagtgaagcagctgagcaggaaaaagggcttccttctgaactctcc ccagctattgaggaagaagagtcaaagagtggcttagatgtcatgcctaatatttctgat gtgctgctgcgcaaactgcgggtccacaggagtctccctggaagtgcccctccactcact gaaaaggaagttgagaacgtgtttgtgcaactgtccttggcctttagaaatgacagctac actctggaatctagaattaaccaggctgaaagggaacgcaacctgacagaggagaacact gagaaagaactggaaaacttcaaagcttccattacgtcctcagcttcactctggcaccac tgtgagcaccgggaaacctaccagaagttgctggaggacatcgctgtcctgcaccgcctg gctgcccgcctctccagccgagctgaggtggtaggcgccgtccgccaggaaaagcgcatg tcgaaagcaacggaagtgatgatgcagtatgtggagaatctaaagaggacgtatgagaag gaccatgcggagctcatggagtttaaaaagcttgcaaatcagaattcaagccgcagctgt ggcccctctgaagatggggtccctcgcacggcacggtccatgtccctcacgctgggaaag aatatgcctcgccggagggtcagcgttgctgtggttcctaagtttaatgccctgaatctg cctggccaaactcccagctcatcatccattccctccttaccagccttgtcggaatcaccc aatgggaaaggcagcctacctgtcacttcagcactgcctgcacttttggaaaatggaaag acaaatggggacccagattgtgaagcctctgctcctgcgctgaccctgagctgcctggag gagcttagtcaggagaccaaggccaggatggaggaagaagcctacagcaagggattccaa gaaggtctaaagaagaccaaagaacttcaagacctgaaggaggaggaggaagaacagaag agtgagagtcctgaggaacctgaagaggtagaagaaactgaggaagaggaaaagggccca agaagcagcaaacttgaagaattggtccatttcttacaagtcatgtatcccaaactgtgt cagcactggcaagtgatctggatgatggctgcagtgatgctggtcttgactgttgtgctg gggctctacaattcctataactcttgtgcagagcaggctgatgggccccttggaagatcc acttgctcggcagcccagagggactcctggtggagctcaggactccagcatgagcagcct acagagcagtag |
Protein Sequence |
>10335 : length: 903 MGMDLTCPFGVSPACGAQASWSIFGADAAEVPGTRGHSQQEAAMPHIPEDEEPPGEPQAA QSPAGQGPPTAGVSCSPTPTIVLTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTAS LTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDS PSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQKGDEADVSSPHPGE PNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPV TNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEP MGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGK LAKAPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELS PAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSY TLESRINQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRL AARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSC GPSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSSIPSLPALSESP NGKGSLPVTSALPALLENGKTNGDPDCEASAPALTLSCLEELSQETKARMEEEAYSKGFQ EGLKKTKELQDLKEEEEEQKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLC QHWQVIWMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQP TEQ |