|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 10397 |
Name | NDRG1 |
Synonym | CAP43|CMT4D|DRG1|GC4|HMSNL|NDR1|NMSL|PROXY1|RIT42|RTP|TARG1|TDD5;N-myc downstream regulated 1;NDRG1;N-myc downstream regulated 1 |
Definition | DRG-1|N-myc downstream-regulated gene 1 protein|differentiation-related gene 1 protein|nickel-specific induction protein Cap43|protein NDRG1|protein regulated by oxygen-1|reducing agents and tunicamycin-responsive protein|tunicamycin-responsive protein |
Position | 8q24.3 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 1 PubMed records as below. |
|
Evidence Status |
Description |
potential | NDRG1 completely inhibits growth in anchorage-independent assays and in vivo supports a biological function as a tumor suppressor in pancreatic cancer. |
| More detail of all 1 literatures about NDRG1 | |
|
Pathways and Diseases |
|
Pathway | Validated targets of C-MYC transcriptional repression;PID Curated;200171 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | HIF-1-alpha transcription factor network;PID Curated;200172 |
Disease | Charcot-Marie-Tooth disease;FunDO |
Disease | Cancer;FunDO |
Disease | Charcot-Marie-Tooth disease, type 4D;OMIM |
|
External Links |
|
Links to Entrez Gene | 10397 |
Links to all GeneRIF Items | 10397 |
Links to iHOP | 10397 |
|
Sequence Information |
|
Nucleotide Sequence |
>10397 : length: 1185 atgtctcgggagatgcaggatgtagacctcgctgaggtgaagcctttggtggagaaaggg gagaccatcaccggcctcctgcaagagtttgatgtccaggagcaggacatcgagacttta catggctctgttcacgtcacgctgtgtgggactcccaagggaaaccggcctgtcatcctc acctaccatgacatcggcatgaaccacaaaacctgctacaaccccctcttcaactacgag gacatgcaggagatcacccagcactttgccgtctgccacgtggacgcccctggccagcag gacggcgcagcctccttccccgcagggtacatgtacccctccatggatcagctggctgaa atgcttcctggagtccttcaacagtttgggctgaaaagcattattggcatgggaacagga gcaggcgcctacatcctaactcgatttgctctaaacaaccctgagatggtggagggcctt gtccttatcaacgtgaacccttgtgcggaaggctggatggactgggccgcctccaagatc tcaggatggacccaagctctgccggacatggtggtgtcccacctttttgggaaggaagaa atgcagagtaacgtggaagtggtccacacctaccgccagcacattgtgaatgacatgaac cccggcaacctgcacctgttcatcaatgcctacaacagccggcgcgacctggagattgag cgaccaatgccgggaacccacacagtcaccctgcagtgccctgctctgttggtggttggg gacagctcgcctgcagtggatgccgtggtggagtgcaactcaaaattggacccaacaaag accactctcctcaagatggcggactgtggcggcctcccgcagatctcccagccggccaag ctcgctgaggccttcaagtacttcgtgcagggcatgggatacatgccctcggctagcatg acccgcctgatgcggtcccgcacagcctctggttccagcgtcacttctctggatggcacc cgcagccgctcccacaccagcgagggcacccgaagccgctcccacaccagcgagggcacc cgcagccgctcgcacaccagcgagggggcccacctggacatcacccccaactcgggtgct gctgggaacagcgccgggcccaagtccatggaggtctcctgctag |
Protein Sequence |
>10397 : length: 394 MSREMQDVDLAEVKPLVEKGETITGLLQEFDVQEQDIETLHGSVHVTLCGTPKGNRPVIL TYHDIGMNHKTCYNPLFNYEDMQEITQHFAVCHVDAPGQQDGAASFPAGYMYPSMDQLAE MLPGVLQQFGLKSIIGMGTGAGAYILTRFALNNPEMVEGLVLINVNPCAEGWMDWAASKI SGWTQALPDMVVSHLFGKEEMQSNVEVVHTYRQHIVNDMNPGNLHLFINAYNSRRDLEIE RPMPGTHTVTLQCPALLVVGDSSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAK LAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLDGTRSRSHTSEGTRSRSHTSEGT RSRSHTSEGAHLDITPNSGAAGNSAGPKSMEVSC |