Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

11010

Name

GLIPR1

Synonym

CRISP7|GLIPR|RTVP1;GLI pathogenesis-related 1;GLIPR1;GLI pathogenesis-related 1

Definition

GLI pathogenesis-related 1 (glioma)|gliPR 1|glioma pathogenesis-related protein 1|protein RTVP-1|related to testis-specific, vespid, and pathogenesis proteins 1|testes-specific vespid and pathogenesis protein 1

Position

12q21.2

Gene Type

protein-coding

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

reviewed

Identification of GLIPR1 tumor suppressor as methylation-silenced gene in acute myeloid leukemia by microarray analysis.

potential

GLIPR1 is a proapoptotic tumor suppressor acting through the ROS-JNK pathway.

reviewed

"RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer."
More detail of all 3 literatures about GLIPR1

Pathways and Diseases

Pathway

Metabolism of lipids and lipoproteins;Reactome;REACT:22258

Disease

Brain tumor;FunDO

Disease

Prostate cancer;FunDO

External Links

Links to Entrez Gene

11010

Links to all GeneRIF Items

11010

Links to iHOP

11010

Sequence Information

Nucleotide Sequence

>11010 : length: 801
atgcgtgtcacacttgctacaatagcctggatggtttcttttgtctccaattattcacac
acagcaaatattttgccagatatcgaaaatgaagatttcatcaaagactgcgttcgaatc
cataacaagttccgatcagaggtgaaaccaacagccagtgatatgctatacatgacttgg
gacccagcactagcccaaattgcaaaagcatgggccagcaattgccagttttcacataat
acacggctgaagccaccccacaagctgcacccaaacttcacttcactgggagagaacatc
tggactgggtctgtgcccattttttctgtgtcttccgccatcacaaactggtatgacgaa
atccaggactatgacttcaagactcggatatgcaaaaaagtctgtggccactacactcag
gttgtttgggcagatagttacaaagttggctgcgcagttcaattttgccctaaagtttct
ggctttgacgctctttccaatggagcacattttatatgcaactacggaccaggagggaat
tacccaacttggccatataagagaggagccacctgcagtgcctgccccaataatgacaag
tgtttggacaatctctgtgttaaccgacagcgagaccaagtcaaacgttactactctgtt
gtatatccaggctggcccatatatccacgtaacagatacacttctctctttctcattgtt
aattcagtaattctaatactgtctgttataattaccattttggtacagcacaagtaccct
aatttagttcttttggactaa

Protein Sequence

>11010 : length: 266
MRVTLATIAWMVSFVSNYSHTANILPDIENEDFIKDCVRIHNKFRSEVKPTASDMLYMTW
DPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGENIWTGSVPIFSVSSAITNWYDE
IQDYDFKTRICKKVCGHYTQVVWADSYKVGCAVQFCPKVSGFDALSNGAHFICNYGPGGN
YPTWPYKRGATCSACPNNDKCLDNLCVNRQRDQVKRYYSVVYPGWPIYPRNRYTSLFLIV
NSVILILSVIITILVQHKYPNLVLLD



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