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| General information | Expression | Regulation | Mutation | Interaction |
Basic Information | |
|---|---|
Gene ID | 11080 |
Name | DNAJB4 |
Synonym | DNAJW|DjB4|HLJ1;DnaJ (Hsp40) homolog, subfamily B, member 4;DNAJB4;DnaJ (Hsp40) homolog, subfamily B, member 4 |
Definition | DnaJ-like heat shock protein 40|HSP40 homolog|dnaJ homolog subfamily B member 4|heat shock 40 kDa protein 1 homolog|heat shock protein 40 homolog|human liver DnaJ-like protein |
Position | 1p31.1 |
Gene Type | protein-coding |
Source | Count: 2; Pubmed_search,Generif |
Literature support | Count: 3 PubMed records as below. |
Evidence Status | Description |
potential | "HLJ1 switches the role of NPM1, which can act as tumor suppressor or oncogene, by modulating the oligomerization of NPM1 via HLJ1-NPM1 heterodimer formation and recruiting AP-2alpha to the MMP-2 promoter." |
reviewed | Curcumin inhibits lung cancer cell invasion and metastasis through the tumor suppressor HLJ1. |
potential | "HLJ1 is a novel tumor suppressor in NSCLC, and high HLJ1 expression is associated with reduced cancer recurrence and prolonged survival of NSCLC patients." |
| More detail of all 3 literatures about DNAJB4 | |
External Links | |
Links to Entrez Gene | 11080 |
Links to all GeneRIF Items | 11080 |
Links to iHOP | 11080 |
Sequence Information | |
Nucleotide Sequence | >11080 : length: 1014 atggggaaagactattattgcattttgggaattgagaaaggagcttcagatgaagatatt aaaaaggcttaccgaaaacaagccctcaaatttcatccggacaagaacaaatctcctcag gcagaggaaaaatttaaagaggtcgcagaagcttatgaagtattgagtgatcctaaaaag agagaaatatatgatcagtttggggaggaagggttgaaaggaggagcaggaggtactgat ggacaaggaggtaccttccggtacacctttcatggcgatcctcatgctacatttgctgca tttttcggagggtccaacccctttgaaattttctttggaagacgaatgggtggtggtaga gattctgaagaaatggaaatagatggtgatccttttagtgcctttggtttcagcatgaat ggatatccaagagacaggaattctgtggggccatcccgcctcaaacaagatcctccagtt attcatgaacttagagtatcacttgaagagatatatagtggttgtaccaaacggatgaag atttctcgaaaaaggctaaacgctgatggaaggagttacagatctgaggacaaaattctt accattgagattaaaaaagggtggaaagaaggcaccaaaattacttttccaagagaagga gatgaaacaccaaatagtattccagcagacattgtttttatcattaaagacaaagatcat ccaaaatttaaaagggatggatcaaatataatttatactgctaaaattagtttacgagag gcattgtgtggctgctcaattaatgtaccaacactggatggaagaaacatacctatgtca gtaaatgatattgtgaaacccggaatgaggagaagaattattggatatgggctgccattt ccaaaaaatcctgaccaacgtggtgaccttctaatagaatttgaggtgtccttcccagat actatatcttcttcatccaaagaagtacttaggaaacatcttcctgcctcatag |
Protein Sequence | >11080 : length: 337 MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKK REIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGR DSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMK ISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDH PKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPF PKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS |