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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 11108 |
Name | PRDM4 |
Synonym | PFM1;PR domain containing 4;PRDM4;PR domain containing 4 |
Definition | PR domain zinc finger protein 4|PR domain-containing protein 4|PR-domain zinc-finger protein PFM1 |
Position | 12q23-q24.1 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
potential | "PFM1 (PRDM4), a new member of the PR-domain family, maps to a tumor suppressor locus on human chromosome 12q23-q24.1. These results suggest a role for PFM1 in cell differentiation and tumor suppression, remarkably consistent with the known functions of the PR-domain family." |
| More detail of all 1 literatures about PRDM4 | |
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Pathways and Diseases |
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Pathway | p75NTR negatively regulates cell cycle via SC1;PID Reactome;500612 |
Pathway | Signalling by NGF;Reactome;REACT:11061 |
Pathway | p75(NTR)-mediated signaling;PID Curated;200103 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
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External Links |
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Links to Entrez Gene | 11108 |
Links to all GeneRIF Items | 11108 |
Links to iHOP | 11108 |
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Sequence Information |
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Nucleotide Sequence |
>11108 : length: 2406 atgcatcacaggatgaatgaaatgaacctgagtccagtggggatggagcagctgacttca tcctctgtgagcaatgccttgccagtctcaggaagtcacctgggattggctgcctcaccc actcacagtgccatccctgccccaggcctcccagtggcaattccaaacctgggtccctcc ctgagctctctgccttctgctctgtctttaatgctaccaatgggtattggggatcgaggg gtgatgtgtgggttacctgaaagaaactacaccctacctccaccaccttaccctcacctg gagagcagttatttcagaaccattctacctggcattttatcttatttagctgacagacca cctccacagtacatccaccctaactctataaatgttgatggtaatacagcattatctatc accaataacccttcagcactagatccctatcagtccaatggaaatgttggattagaacca ggcattgtttcaatagactctcgctctgtgaacacacatggtgcccaaagtcttcatccc agtgatggccatgaggtggccttggacacagcaatcactatggagaacgtttctagggtt accagcccaatttcgacagatggaatggcagaggagcttacgatggacggtgttgcaggc gagcattcccaaatcccaaatggctccagaagtcatgaacctctgtctgtggattctgtg agcaacaaccttgcagcagacgctgtaggacatggtggtgtgatacccatgcatgggaat ggcctggagctccctgtggtcatggagacagaccacattgcaagtcgggtcaatggcatg tctgacagtgccctcagtgactccattcacactgtggccatgagcaccaactctgtaagc gtggcactctctacctcacacaaccttgcctccctagaatctgtttccctccatgaagtt ggcctcagcctagaacctgtggctgtctcctccatcacccaggaggttgctatggggaca ggtcatgtagatgtatcttcagacagtctttcttttgtatcaccttcactgcaaatggaa gactccaattcaaacaaggagaacatggcaaccttgtttacaatttggtgtactctgtgt gaccgcgcctatccctcggactgtcccgaacatggaccagtgacttttgttcctgacact ccaatagagagcagagcaaggctttctctcccaaagcagcttgttctccgtcagtcaatt gtgggagcagaagttggtgtatggactggagaaaccattcctgtgcggacttgctttgga cctctaattggccagcagagtcactccatggaagtagcagaatggacagacaaggcagtt aaccatatctggaagatataccacaatggtgtcctagaattctgcatcattacaactgat gaaaatgaatgtaattggatgatgtttgtgcgcaaagccaggaaccgggaagagcagaat ttggtggcttatcctcatgatggaaaaatctttttctgcacctcacaagatatccctcct gaaaatgaactgcttttttattatagccgagattatgctcaacagattggtgttcctgaa cacccagatgtgcatctctgtaactgtggcaaggagtgcaattcttacacagagttcaaa gcccatctgaccagccacatccataaccatcttcctacccagggacatagcggcagccat gggccaagtcacagcaaagaaaggaagtggaagtgctcaatgtgcccccaagcttttatc tctccttccaaacttcatgtccactttatgggtcacatgggtatgaagccccacaagtgt gatttctgtagcaaggcttttagtgatcccagcaacctgcggacccacctcaagatacat acaggtcagaagaactacaggtgtaccttgtgtgacaagtctttcacccagaaggctcac ctggagtcccacatggttatccacactggggagaagaatcttaagtgtgattactgtgac aagttgtttatgcggaggcaggacctcaagcagcacgtgctcatccacactcaagaacgc cagatcaagtgtcccaagtgtgataagctgttcttgagaacaaatcacttaaagaagcat ctcaattctcatgaaggaaaacgggattatgtctgtgaaaaatgtacaaaggcttatcta accaaataccatctcacccgccacctgaaaacctgcaaagggcccacctccagttcgtca gcaccagaggaggaagaagaggatgactcagaagaggaagatctagcagactctgtgggg acagaagactgtaggattaacagtgctgtgtattcagcggatgagtctctttctgcacat aaataa |
Protein Sequence |
>11108 : length: 801 MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPS LSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRP PPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHP SDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSV SNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVS VALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQME DSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSI VGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTD ENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPE HPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFI SPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAH LESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKH LNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVG TEDCRINSAVYSADESLSAHK |