Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

112464

Name

PRKCDBP

Synonym

CAVIN3|HSRBC|SRBC|cavin-3;protein kinase C, delta binding protein;PRKCDBP;protein kinase C, delta binding protein

Definition

protein kinase C delta-binding protein|sdr-related gene product that binds to c-kinase|serum deprivation response factor-related gene product that binds to C-kinase

Position

11p15.4

Gene Type

protein-coding

Source

Count: 2; Generif,UniProt

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

reviewed

"hSRBC is a novel tumor suppressor whose epigenetic inactivation contributes to the malignant progression of gastric tumors, in part, through attenuated p53 response to stresses."

potential

"hSRBC is a candidate tumor suppressor gene involved in lung cancer pathogenesis, where expression is frequently inactivated by methylation and other mechanisms".

reviewed

Human SRBC is located within the 11p15.5-p15.4 tumor suppressor region and is inactivated in breast and lung cancers.
More detail of all 3 literatures about PRKCDBP

External Links

Links to Entrez Gene

112464

Links to all GeneRIF Items

112464

Links to iHOP

112464

Sequence Information

Nucleotide Sequence

>112464 : length: 786
atgagggagagtgcgttggagcgggggcctgtgcccgaggcgccggcggggggtcccgtg
cacgccgtgacggtggtgaccctgctggagaagctggcctccatgctggagactctgcgg
gagcggcagggaggcctggctcgaaggcagggaggcctggcagggtccgtgcgccgcatc
cagagcggcctgggcgctctgagtcgcagccacgacaccaccagcaacaccttggcgcag
ctgctggccaaggcggagcgcgtgagctcgcacgccaacgccgcccaagagcgcgcggtg
cgccgcgcagcccaggtgcagcggctggaggccaaccacgggctgctggtggcgcgcggg
aagctccacgttctgctcttcaaggaggagggtgaagtcccagccagcgctttccagaag
gcaccagagcccttgggcccggcggaccagtccgagctgggcccagagcagctggaggcc
gaagttggagagagctcggacgaggagccggtggagtccagggcccagcggctgcggcgc
accggattgcagaaggtacagagcctccgaagggccctttcgggccggaaaggccctgca
gcgccaccgcccaccccggtcaagccgcctcgccttgggcctggccggagcgctgaagcc
cagccggaagcccagcctgcgctggagcccacgctggagccagagcctccgcaggacacc
gaggaagatcccgggagacctggggctgccgaagaagctctgctccaaatggagagtgta
gcctga

Protein Sequence

>112464 : length: 261
MRESALERGPVPEAPAGGPVHAVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRI
QSGLGALSRSHDTTSNTLAQLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARG
KLHVLLFKEEGEVPASAFQKAPEPLGPADQSELGPEQLEAEVGESSDEEPVESRAQRLRR
TGLQKVQSLRRALSGRKGPAAPPPTPVKPPRLGPGRSAEAQPEAQPALEPTLEPEPPQDT
EEDPGRPGAAEEALLQMESVA



Copyright © 2016-Present - The Univsersity of Texas Health Science Center at Houston Rights Reserved
Site Policies | State of Texas