Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

114907

Name

FBXO32

Synonym

Fbx32|MAFbx;F-box protein 32;FBXO32;F-box protein 32

Definition

F-box only protein 32|atrogin 1|atrogin-1|muscle atrophy F-box protein

Position

8q24.13

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

reviewed

"The novel tumor suppressor FBXO32 is epigenetically silenced in ovarian cancer cell lines with disrupted TGF-beta/SMAD4 signaling, and FBXO32 methylation status predicts survival in patients with ovarian cancer."
More detail of all 1 literatures about FBXO32

Pathways and Diseases

Pathway

FoxO family signaling;PID Curated;200091

External Links

Links to Entrez Gene

114907

Links to all GeneRIF Items

114907

Links to iHOP

114907

Sequence Information

Nucleotide Sequence

>114907 : length: 1068
atgccattcctcgggcaggactggcggtcccccgggcagaactgggtgaagacggccgac
ggctggaagcgcttcctggatgagaagagcggcagtttcgtgagcgacctcagcagttac
tgcaacaaggaggtatacaataaggagaatcttttcaacagcctgaactatgatgttgca
gccaagaagagaaagaaggacatgctgaatagcaaaaccaaaactcagtatttccaccaa
gaaaaatggatctatgttcacaaaggaagtactaaagagcgccatggatattgcaccctg
ggggaagctttcaacagactggacttctcaactgccattctggattccagaagatttaac
tacgtggtccggctgttggagctgatagcaaagtcacagctcacatccctgagtggcatc
gcccaaaagaacttcatgaatattttggaaaaagtggtactgaaagtccttgaagaccag
caaaacattagactaataagggaactactccagaccctctacacatccttatgtacactg
gtccaaagagtcggcaagtctgtgctggtcgggaacattaacatgtgggtgtatcggatg
gagacgattctccactggcagcagcagctgaacaacattcagatcaccaggcctgccttc
aaaggcctcaccttcactgacctgcctttgtgcctacaactgaacatcatgcagaggctg
agcgacgggcgggacctggtcagcctgggccaggctgcccccgacctgcacgtgctcagc
gaagaccggctgctgtggaagaaactctgccagtaccacttctccgagcggcagatccgc
aaacgattaattctgtcagacaaagggcagctggattggaagaagatgtatttcaaactt
gtccgatgttacccaaggaaagagcagtatggagatacccttcagctctgcaaacactgt
cacatcctttcctggaagggcactgaccatccgtgcactgccaataacccagagagctgc
tccgtttcactttcaccccaggactttatcaacttgttcaagttctga

Protein Sequence

>114907 : length: 355
MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA
AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN
YVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTL
VQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRL
SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL
VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF



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