Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

115761

Name

ARL11

Synonym

ARLTS1;ADP-ribosylation factor-like 11;ARL11;ADP-ribosylation factor-like 11

Definition

ADP-ribosylation factor-like protein 11|ADP-ribosylation factor-like tumor suppressor protein 1

Position

13q14.2

Gene Type

protein-coding

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

reviewed

"The role of the allelic variants in ARLTS1, RAD51 and MDM2 acting in the tumor suppressor, DNA repair and p53 pathways as risk factors for familial breast cancer in 147 patients displaying characteristics of familial disease, was investigated."

reviewed

A novel tumor suppressor gene [ARLTS1 (ADP-ribosylation factor-like tumor suppressor gene 1)]is found to be altered in human carcinogenesis. It is located in Chromosome 13q14.3.

reviewed

tumor suppressor functions of ARLTS1 in lung cancers.
More detail of all 3 literatures about ARL11

External Links

Links to Entrez Gene

115761

Links to all GeneRIF Items

115761

Links to iHOP

115761

Sequence Information

Nucleotide Sequence

>115761 : length: 591
atgggttctgtgaattccagaggtcacaaggcggaagcccaggtggtgatgatgggcctg
gactcggcgggcaagaccacgctcctttacaagctgaagggccaccagctggtggagacc
ctgcccactgttggtttcaacgtggagcctctgaaagctcctgggcacgtgtcactgact
ctctgggacgttggggggcaggccccgctcagagccagctggaaggactatctggaaggc
acagatatcctcgtgtacgtgctggacagcacagatgaagcccgcttacccgagtcggcg
gctgagctcacagaagtcctgaacgaccccaacatggctggcgtccccttcttggtgctg
gccaacaagcaggaggcacctgatgcacttccgctgcttaagatcagaaacaggctgagt
ctagagagattccaggaccactgctgggagctccggggctgcagtgccctcactggggag
gggctgcccgaggccctgcagagcctgtggagcctcctgaaatctcgcagctgcatgtgt
ctgcaggcgagagcccatggggctgagcgcggagacagcaagagatcttga

Protein Sequence

>115761 : length: 196
MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFNVEPLKAPGHVSLT
LWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVLNDPNMAGVPFLVL
ANKQEAPDALPLLKIRNRLSLERFQDHCWELRGCSALTGEGLPEALQSLWSLLKSRSCMC
LQARAHGAERGDSKRS



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