Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

116135

Name

LRRC3B

Synonym

LRP15;leucine rich repeat containing 3B;LRRC3B;leucine rich repeat containing 3B

Definition

leucine-rich repeat protein LRP15|leucine-rich repeat-containing protein 3B

Position

3p24

Gene Type

protein-coding

Source

Count: 2; Pubmed_search,Generif

Literature support

Count: 3 PubMed records as below.

Evidence Status

Description

potential

Methylation pattern of the putative tumor-suppressor gene LRRC3B promoter in clear cell renal cell carcinomas.

potential

LRRC3B may be a novel methylation-sensitive tumor suppressor gene in CRC. LRRC3B methylation has significant tumor specificity and may be a biomarker of CRC.

potential

suggest that LRRC3B is a putative tumor suppressor gene that is silenced in gastric cancers by epigenetic mechanisms and that LRRC3B silencing in cancer may play an important role in tumor escape from immune surveillance.
More detail of all 3 literatures about LRRC3B

External Links

Links to Entrez Gene

116135

Links to all GeneRIF Items

116135

Links to iHOP

116135

Sequence Information

Nucleotide Sequence

>116135 : length: 780
atgaatctggtagacctgtggttaacccgttccctctccatgtgtctcctcctacaaagt
tttgttcttatgatactgtgctttcattctgccagtatgtgtcccaagggctgtctttgt
tcttcctctgggggtttaaatgtcacctgtagcaatgcaaatctcaaggaaatacctaga
gatcttcctcctgaaacagtcttactgtatctggactccaatcagatcacatctattccc
aatgaaatttttaaggacctccatcaactgagagttctcaacctgtccaaaaatggcatt
gagtttatcgatgagcatgccttcaaaggagtagctgaaaccttgcagactctggacttg
tccgacaatcggattcaaagtgtgcacaaaaatgccttcaataacctgaaggccagggcc
agaattgccaacaacccctggcactgcgactgtactctacagcaagttctgaggagcatg
gcgtccaatcatgagacagcccacaacgtgatctgtaaaacgtccgtgttggatgaacat
gctggcagaccattcctcaatgctgccaacgacgctgacctttgtaacctccctaaaaaa
actaccgattatgccatgctggtcaccatgtttggctggttcactatggtgatctcatat
gtggtatattatgtgaggcaaaatcaggaggatgcccggagacacctcgaatacttgaaa
tccctgccaagcaggcagaagaaagcagatgaacctgatgatattagcactgtggtatag

Protein Sequence

>116135 : length: 259
MNLVDLWLTRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPR
DLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDL
SDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDEH
AGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLK
SLPSRQKKADEPDDISTVV



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