|
|
||
|
|
||
| General information | Expression | Regulation | Mutation | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 1601 |
Name | DAB2 |
Synonym | DOC-2|DOC2;disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila);DAB2;disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) |
Definition | differentially-expressed protein 2|disabled homolog 2 |
Position | 5p13 |
Gene Type | protein-coding |
Source | Count: 3; Pubmed_search,TAG,Generif |
Literature support | Count: 2 PubMed records as below. |
|
Evidence Status |
Description |
potential | "DOC-2, a candidate tumor suppressor gene in human epithelial ovarian cancer." |
potential | "DAB2 acts as a tumor suppressor by dictating tumor cell TGF-beta responses, identify a biomarker for squamous cell carcinomas progression." |
| More detail of all 2 literatures about DAB2 | |
|
Pathways and Diseases |
|
Pathway | Membrane Trafficking;Reactome;REACT:11123 |
Pathway | Endocytosis;KEGG PATHWAY;hsa04144 |
Pathway | TGF-beta receptor signaling;PID Curated;200195 |
Disease | Chronic kidney disease;NHGRI |
Disease | Cancer;FunDO |
|
External Links |
|
Links to Entrez Gene | 1601 |
Links to all GeneRIF Items | 1601 |
Links to iHOP | 1601 |
|
Sequence Information |
|
Nucleotide Sequence |
>1601 : length: 2313 atgtctaacgaagtagaaacaagtgcaaccaatggtcagcccgaccaacaggccgcacca aaagcaccctcaaagaaggaaaaaaagaaaggccctgaaaagacagatgaatatctctta gcaaggttcaaaggcgatggtgtaaaatataaggccaagctgattggcattgatgatgtg ccagatgcaagaggggataaaatgagccaagactctatgatgaaactaaagggaatggcg gcagctggtcggtctcagggacaacacaaacaaaggatctgggtcaacatttccctttct gggataaaaataattgatgagaaaactggggtaatagagcatgaacatccagtaaataag atttctttcattgcccgtgatgtgacagacaaccgggcatttggttacgtgtgtggagga gaaggccagcatcagttttttgccataaaaaccgggcaacaggctgaaccattagttgtt gatcttaaagacctttttcaagttatctataatgtaaagaaaaaggaagaagaaaagaaa aagatagaggaagccagcaaagcagttgagaatgggagtgaggccctaatgattctagat gaccaaactaacaaactgaaatcgggtgttgaccagatggatttgtttggggacatgtct acacctcctgacctaaatagtccaacagaaagcaaagatatcctgttagtggatctaaac tctgaaatcgacaccaatcagaattctttaagagaaaatccattcttaacaaacggcatc acctcctgttctcttcctcgaccaacgcctcaggcatccttcttgcctgaaaatgccttt tctgccaatctcaacttctttcccacccctaatcctgatcctttccgtgacgatcctttc acacagccagaccaatcgacaccttcttcgtttgattctctcaaatctccagatcagaag aaagagaattcgagtagctcgtctactccgctgagtaatgggcccctgaatggtgatgtt gactactttggtcagcaatttgaccagatctctaaccggactggcaaacaggaagctcag gcaggcccatggcccttttcaagttcgcaaacccagccagcagtgagaactcaaaatggg gtatctgaaagagaacagaacggcttctctgtcaaatcctccccgaacccttttgtggga agccctcccaaaggactgtccatacagaatggcgtaaagcaggacttggaaagctctgtc cagtcctcaccacatgactccatagccattatcccacctccacaaagtaccaaaccagga agaggcagaaggactgctaagtcttcagccaatgacttgcttgcatcagacatctttgct cctcccgtctcagaaccttcaggccaggcgtcacccacaggacaacctacagccctgcag cccaaccctctggatctcttcaaaacaagtgctcctgccccagtggggcccctggtgggt ctaggtggtgtaactgtcacactccctcaggcaggaccatggaacacagcatctttggtc ttcaatcagtccccttcaatggctccgggagccatgatgggtggtcaaccttcaggtttt agtcagcccgtcatttttggtacaagtccagctgtttcaggttggaaccagccttcaccc tttgcagcctcaactccccctccagtgcctgttgtctggggcccttctgcatctgtggca cccaatgcttggtcaacaacaagccctttggggaatccttttcagagcaatatttttcca gctcctgctgtgtccactcagcccccatccatgcactcctctctcctggtcactcctcct cagccacctcccagagctggccctcccaaggacatctccagtgatgccttcactgcctta gacccacttggggataaagagatcaaggatgtgaaagaaatgtttaaggatttccaactg cggcagccacctgctgtgcccgcgcggaagggagagcagacttcttctgggactttgagt gcctttgccagttatttcaacagcaaggttggcattcctcaggagaatgcagaccatgat gactttgatgctaatcaactattgaacaagatcaatgaaccaccaaagccagctcccaga caagtttccctgccagttaccaaatctactgacaatgcatttgagaaccctttctttaaa gattcttttggttcatcacaagcctctgtggcttcttctcaacctgtatcttctgagatg tatagggatccatttggaaatccttttgcctaa |
Protein Sequence |
>1601 : length: 770 MSNEVETSATNGQPDQQAAPKAPSKKEKKKGPEKTDEYLLARFKGDGVKYKAKLIGIDDV PDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKTGVIEHEHPVNK ISFIARDVTDNRAFGYVCGGEGQHQFFAIKTGQQAEPLVVDLKDLFQVIYNVKKKEEEKK KIEEASKAVENGSEALMILDDQTNKLKSGVDQMDLFGDMSTPPDLNSPTESKDILLVDLN SEIDTNQNSLRENPFLTNGITSCSLPRPTPQASFLPENAFSANLNFFPTPNPDPFRDDPF TQPDQSTPSSFDSLKSPDQKKENSSSSSTPLSNGPLNGDVDYFGQQFDQISNRTGKQEAQ AGPWPFSSSQTQPAVRTQNGVSEREQNGFSVKSSPNPFVGSPPKGLSIQNGVKQDLESSV QSSPHDSIAIIPPPQSTKPGRGRRTAKSSANDLLASDIFAPPVSEPSGQASPTGQPTALQ PNPLDLFKTSAPAPVGPLVGLGGVTVTLPQAGPWNTASLVFNQSPSMAPGAMMGGQPSGF SQPVIFGTSPAVSGWNQPSPFAASTPPPVPVVWGPSASVAPNAWSTTSPLGNPFQSNIFP APAVSTQPPSMHSSLLVTPPQPPPRAGPPKDISSDAFTALDPLGDKEIKDVKEMFKDFQL RQPPAVPARKGEQTSSGTLSAFASYFNSKVGIPQENADHDDFDANQLLNKINEPPKPAPR QVSLPVTKSTDNAFENPFFKDSFGSSQASVASSQPVSSEMYRDPFGNPFA |