Bioinformatics and Systems Medicine Laboratory
General information | Expression | Regulation | Mutation | Interaction

Basic Information

Gene ID

1946

Name

EFNA5

Synonym

AF1|EFL5|EPLG7|GLC1M|LERK7|RAGS;ephrin-A5;EFNA5;ephrin-A5

Definition

AL-1|LERK-7|eph-related receptor tyrosine kinase ligand 7

Position

5q21

Gene Type

protein-coding

Source

Count: 1; Generif

Literature support

Count: 1 PubMed records as below.

Evidence Status

Description

reviewed

"ephrinA5 acted as a tumor suppressor in glioma, and its negative regulation of EGFR contributed to the suppressive effects."
More detail of all 1 literatures about EFNA5

Pathways and Diseases

Pathway

Axon guidance;KEGG PATHWAY;hsa04360

Pathway

EPHA forward signaling;PID Curated;200121

Pathway

EphrinA-EPHA pathway;PID Curated;200040

Pathway

EPHB forward signaling;PID Curated;200041

Pathway

Ephrin A reverse signaling;PID Curated;200048

Disease

hippocampal atrophy;GAD

Disease

Hippocampal atrophy;NHGRI

Disease

NEUROLOGICAL;GAD

External Links

Links to Entrez Gene

1946

Links to all GeneRIF Items

1946

Links to iHOP

1946

Sequence Information

Nucleotide Sequence

>1946 : length: 687
atgttgcacgtggagatgttgacgctggtgtttctggtgctctggatgtgtgtgttcagc
caggacccgggctccaaggccgtcgccgaccgctacgctgtctactggaacagcagcaac
cccagattccagaggggtgactaccatattgatgtctgtatcaatgactacctggatgtt
ttctgccctcactatgaggactccgtcccagaagataagactgagcgctatgtcctctac
atggtgaactttgatggctacagtgcctgcgaccacacttccaaagggttcaagagatgg
gaatgtaaccggcctcactctccaaatggaccgctgaagttctctgaaaaattccagctc
ttcactcccttttctctaggatttgaattcaggccaggccgagaatatttctacatctcc
tctgcaatcccagataatggaagaaggtcctgtctaaagctcaaagtctttgtgagacca
acaaatagctgtatgaaaactataggtgttcatgatcgtgttttcgatgttaacgacaaa
gtagaaaattcattagaaccagcagatgacaccgtacatgagtcagccgagccatcccgc
ggcgagaacgcggcacaaacaccaaggatacccagccgccttttggcaatcctactgttc
ctcctggcgatgcttttgacattatag

Protein Sequence

>1946 : length: 228
MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDV
FCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQL
FTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDK
VENSLEPADDTVHESAEPSRGENAAQTPRIPSRLLAILLFLLAMLLTL



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