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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 2041 |
Name | EPHA1 |
Synonym | EPH|EPHT|EPHT1;EPH receptor A1;EPHA1;EPH receptor A1 |
Definition | eph tyrosine kinase 1|ephrin type-A receptor 1|erythropoietin-producing hepatoma amplified sequence|erythropoietin-producing hepatoma receptor|hEpha1|oncogene EPH|soluble EPHA1 variant 1|soluble EPHA1 variant 2|tyrosine-protein kinase receptor EPH |
Position | 7q34 |
Gene Type | protein-coding |
Source | Count: 1; Generif |
Literature support | Count: 1 PubMed records as below. |
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Evidence Status |
Description |
reviewed | "The present study reveals a novel function for EphA1 and EphB2 in the induction of autophagy, suggesting a tumor suppressor role for these proteins in colorectal cancer." |
potential | "The present study reveals a novel function for EphA1 and EphB2 in the induction of autophagy, suggesting a tumor suppressor role for these proteins in colorectal cancer." |
| More detail of all 1 literatures about EPHA1 | |
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Pathways and Diseases |
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Pathway | Axon guidance;KEGG PATHWAY;hsa04360 |
Disease | Cervical cancer;FunDO |
Disease | Ovarian cancer;FunDO |
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External Links |
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Links to Entrez Gene | 2041 |
Links to all GeneRIF Items | 2041 |
Links to iHOP | 2041 |
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Sequence Information |
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Nucleotide Sequence |
>2041 : length: 2931 atggagcggcgctggcccctggggctagggctggtgctgctgctctgcgccccgctgccc ccgggggcgcgcgccaaggaagttactctgatggacacaagcaaggcacagggagagctg ggctggctgctggatcccccaaaagatgggtggagtgaacagcaacagatactgaatggg acacccctgtacatgtaccaggactgcccaatgcaaggacgcagagacactgaccactgg cttcgctccaattggatctaccgcggggaggaggcttcccgcgtccacgtggagctgcag ttcaccgtgcgggactgcaagagtttccctgggggagccgggcctctgggctgcaaggag accttcaaccttctgtacatggagagtgaccaggatgtgggcattcagctccgacggccc ttgttccagaaggtaaccacggtggctgcagaccagagcttcaccattcgagaccttgtg tctggctccgtgaagctgaatgtggagcgctgctctctgggccgcctgacccgccgtggc ctctacctcgctttccacaacccgggtgcctgtgtggccctggtgtctgtccgggtcttc taccagcgctgtcctgagaccctgaatggcttggcccaattcccagacactctgcctggc cccgctgggttggtggaagtggcggggacctgcttgccccacgcgcgggccagccccagg ccctcaggtgcaccccgcatgcactgcagccctgatggcgagtggctggtgcctgtagga cggtgccactgtgagcctggctatgaggaaggtggcagtggcgaagcatgtgttgcctgc cctagcggctcctaccggatggacatggacacaccccattgtctcacgtgcccccagcag agcactgctgagtctgagggggccaccatctgtacctgtgagagcggccattacagagct cccggggagggcccccaggtggcatgcacaggtcccccctcggccccccgaaacctgagc ttctctgcctcagggactcagctctccctgcgttgggaacccccagcagatacgggggga cgccaggatgtcagatacagtgtgaggtgttcccagtgtcagggcacagcacaggacggg gggccctgccagccctgtggggtgggcgtgcacttctcgccgggggcccgggggctcacc acacctgcagtgcatgtcaatggccttgaaccttatgccaactacacctttaatgtggaa gcccaaaatggagtgtcagggctgggcagctctggccatgccagcacctcagtcagcatc agcatggggcatgcagagtcactgtcaggcctgtctctgagactggtgaagaaagaaccg aggcaactagagctgacctgggcggggtcccggccccgaagccctggggcgaacctgacc tatgagctgcacgtgctgaaccaggatgaagaacggtaccagatggttctagaacccagg gtcttgctgacagagctgcagcctgacaccacatacatcgtcagagtccgaatgctgacc ccactgggtcctggccctttctcccctgatcatgagtttcggaccagcccaccagtgtcc aggggcctgactggaggagagattgtagccgtcatctttgggctgctgcttggtgcagcc ttgctgcttgggattctcgttttccggtccaggagagcccagcggcagaggcagcagagg cagcgtgaccgcgccaccgatgtggatcgagaggacaagctgtggctgaagccttatgtg gacctccaggcatacgaggaccctgcacagggagccctggactttacccgggagcttgat ccagcgtggctgatggtggacactgtcataggagaaggagagtttggggaagtgtatcga gggaccctgaggctccccagccaggactgcaagactgtggccattaagaccttaaaagac acatccccaggtggccagtggtggaacttccttcgagaggcaactatcatgggccagttt agccacccgcatattctgcatctggaaggcgtcgtcacaaagcgaaagccgatcatgatc atcacagaatttatggagaatggagccctggatgccttcctgagggagcgggaggaccag ctggtccctgggcagctagtggccatgctgcagggcatagcatctggcatgaactacctc agtaatcacaattatgtccaccgggacctggctgccagaaacatcttggtgaatcaaaac ctgtgctgcaaggtgtctgactttggcctgactcgcctcctggatgactttgatggcaca tacgaaacccagggaggaaagatccctatccgttggacagcccctgaagccattgcccat cggatcttcaccacagccagcgatgtgtggagctttgggattgtgatgtgggaggtgctg agctttggggacaagccttatggggagatgagcaatcaggaggttatgaagagcattgag gatgggtaccggttgccccctcctgtggactgccctgcccctctgtatgagctcatgaag aactgctgggcatatgaccgtgcccgccggccacacttccagaagcttcaggcacatctg gagcaactgcttgccaacccccactccctgcggaccattgccaactttgaccccaggatg actcttcgcctgcccagcctgagtggctcagatgggatcccatatcgaaccgtctctgag tggctcgagtccatacgcatgaaacgctacatcctgcacttccactcggctgggctggac accatggagtgtgtgctggagctgaccgctgaggacctgacgcagatgggaatcacactg cccgggcaccagaagcgcattctttgcagtattcagggattcaaggactga |
Protein Sequence |
>2041 : length: 976 MERRWPLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG TPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKE TFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRG LYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVAGTCLPHARASPR PSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQ STAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGG RQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVE AQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLT YELHVLNQDEERYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVS RGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYV DLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKD TSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQ LVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGT YETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE DGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRM TLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITL PGHQKRILCSIQGFKD |