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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 2077 |
Name | ERF |
Synonym | PE-2|PE2;Ets2 repressor factor;ERF;Ets2 repressor factor |
Definition | ETS domain-containing transcription factor ERF |
Position | 19q13 |
Gene Type | protein-coding |
Source | Count: 2; TAG,Generif |
Literature support | Count: 2 PubMed records as below. |
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Evidence Status |
Description |
potential | "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation." |
potential | ERF is a ubiquitously expressed ets domain transcriptional repressor with tumor suppressor activity that is regulated by the Ras/Erk signaling pathway. |
| More detail of all 2 literatures about ERF | |
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Pathways and Diseases |
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Pathway | PDGF signaling pathway;PANTHER;P00047 |
Disease | Leukemia;FunDO |
Disease | Down syndrome;FunDO |
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External Links |
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Links to Entrez Gene | 2077 |
Links to all GeneRIF Items | 2077 |
Links to iHOP | 2077 |
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Sequence Information |
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Nucleotide Sequence |
>2077 : length: 1647 atgaagaccccggcggacacagggtttgccttcccggattgggcctacaagccagagtcg tcccctggctcaaggcagatccagctgtggcactttatcctggagctgctgcggaaggag gagtaccagggcgtcattgcctggcagggggactacggggaattcgtcatcaaagaccct gatgaggtggcccggctgtggggcgttcgcaagtgcaagccccagatgaattacgacaag ctgagccgggccctgcgctattactataacaagcgcattctgcacaagaccaaggggaaa cggttcacctacaagttcaatttcaacaaactggtgctggtcaattacccattcattgat gtggggttggctgggggtgcagtgccccagagtgccccgccagtgccgtcgggtggtagc cacttccgcttccctccctcaacgccctccgaggtgctgtcccccaccgaggacccccgc tcaccaccagcctgctcttcatcttcatcttccctcttctcggctgtggtggcccgccgc ctgggccgaggctcagtcagtgactgtagtgatggcacgtcagagctggaggaaccgctg ggagaggatccccgcgcccgaccacccggccctccggatctgggtgccttccgagggccc ccgctggcccgcctgccccatgaccctggtgtcttccgagtctatccccggcctcggggt ggccctgaacccctcagccccttccctgtgtcgcctctggccggtcctggatccctgctg ccccctcagctctccccggctctgcccatgacgcccacccacctggcctacactccctcg cccacgctgagcccgatgtaccccagtggtggcggggggcccagcggctcagggggaggc tcccacttctccttcagccctgaggacatgaaacggtacctgcaggcccacacccaaagc gtctacaactaccacctcagcccccgcgccttcctgcactaccctgggctggtggtgccc cagccccagcgccctgacaagtgcccgctgccgcccatggcacccgagaccccaccggtc ccctcctcggcctcgtcatcctcttcttcttcttcctccccattcaagtttaagctccag ccgcccccactcggacgccggcagcgggcagctggggagaaggccgtagccggtgctgac aagagcggtggcagtgcaggcgggctggctgagggggcaggggcgctagccccaccgccc ccgccaccacagatcaaggtggagcccatctcggaaggcgagtcggaggaggtagaggtg actgacatcagtgatgaggatgaggaagacggggaggtgttcaagacgccccgtgcccca cctgcaccccctaagcctgagcccggcgaggcacccggggcatcccagtgcatgcccctc aagctacgctttaagcggcgctggagtgaagactgtcgcctcgaagggggtgggggcccc gctgggggctttgaggatgagggtgaggacaagaaggtgcgtggggaggggcctggggag gctggggggcccctcaccccaaggcgggtgagctctgacctccagcatgccacggcccag ctctccctggagcaccgagactcctga |
Protein Sequence |
>2077 : length: 548 MKTPADTGFAFPDWAYKPESSPGSRQIQLWHFILELLRKEEYQGVIAWQGDYGEFVIKDP DEVARLWGVRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVLVNYPFID VGLAGGAVPQSAPPVPSGGSHFRFPPSTPSEVLSPTEDPRSPPACSSSSSSLFSAVVARR LGRGSVSDCSDGTSELEEPLGEDPRARPPGPPDLGAFRGPPLARLPHDPGVFRVYPRPRG GPEPLSPFPVSPLAGPGSLLPPQLSPALPMTPTHLAYTPSPTLSPMYPSGGGGPSGSGGG SHFSFSPEDMKRYLQAHTQSVYNYHLSPRAFLHYPGLVVPQPQRPDKCPLPPMAPETPPV PSSASSSSSSSSSPFKFKLQPPPLGRRQRAAGEKAVAGADKSGGSAGGLAEGAGALAPPP PPPQIKVEPISEGESEEVEVTDISDEDEEDGEVFKTPRAPPAPPKPEPGEAPGASQCMPL KLRFKRRWSEDCRLEGGGGPAGGFEDEGEDKKVRGEGPGEAGGPLTPRRVSSDLQHATAQ LSLEHRDS |