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| General information | Expression | Regulation | Mutation | Interaction |
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Basic Information |
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|---|---|
Gene ID | 2195 |
Name | FAT1 |
Synonym | CDHF7|CDHR8|FAT|ME5|hFat1;FAT tumor suppressor homolog 1 (Drosophila);FAT1;FAT tumor suppressor homolog 1 (Drosophila) |
Definition | FAT tumor suppressor 1|cadherin ME5|cadherin family member 7|cadherin-related family member 8|cadherin-related tumor suppressor homolog|protein fat homolog|protocadherin Fat 1 |
Position | 4q35 |
Gene Type | protein-coding |
Source | Count: 3; Pubmed_search,TAG,Generif |
Literature support | Count: 3 PubMed records as below. |
|
Evidence Status |
Description |
potential | Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene 'FAT' in human astrocytic tumors. |
reviewed | Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array. |
reviewed | "Fath, the murine homolog of the Drosophila fat tumor suppressor gene, maps to chromosome 8." |
| More detail of all 3 literatures about FAT1 | |
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Pathways and Diseases |
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Pathway | Wnt signaling pathway;PANTHER;P00057 |
Pathway | Cadherin signaling pathway;PANTHER;P00012 |
Disease | Bipolar disorder;FunDO |
Disease | Squamous cell cancer;FunDO |
Disease | Oral cancer;FunDO |
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External Links |
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Links to Entrez Gene | 2195 |
Links to all GeneRIF Items | 2195 |
Links to iHOP | 2195 |
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Sequence Information |
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Nucleotide Sequence |
>2195 : length: 13767 atggggagacatttggctttgctcctgcttctgctccttctcttccaacattttggagac agtgatggcagccaacgacttgaacagactcctctgcagtttacacacctcgagtacaac gtcaccgtgcaggagaactctgcagctaagacttatgtggggcatcctgtcaagatgggt gtttacattacacatccagcgtgggaagtaaggtacaaaattgtttccggagacagtgaa aacctgttcaaagctgaagagtacattctcggagacttttgctttctaagaataaggacc aaaggaggaaatacagctattcttaatagagaagtgaaggatcactacacattgatagtg aaagcacttgaaaaaaatactaatgtggaggcgcgaacaaaggtcagggtgcaggtgctg gatacaaatgacttgagaccgttattctcacccacctcatacagcgtttctttacctgaa aacacagctataaggaccagtatcgcaagagtcagcgccacggatgcagacataggaacc aacggggaattttactacagttttaaagatcgaacagatatgtttgctattcacccaacc agtggtgtgatagtgttaactggtagacttgattacctagagaccaagctctatgagatg gaaatcctcgctgcggaccgtggcatgaagttgtatgggagcagtggcatcagcagcatg gccaagctaacggtgcacatcgaacaggccaatgaatgtgctccggtgataacagcagtg acattgtcaccatcagaactggacagggacccagcatatgcaattgtgacagtggatgac tgcgatcagggtgccaatggtgacatagcatctttaagcatcgtggcaggtgaccttctc cagcagtttagaacagtgaggtcctttccagggagtaaggagtataaagtcaaagccatc ggtggcattgattgggacagtcatcctttcggctacaatctcacactacaggctaaagat aaaggaactccgccccagttctcttctgttaaagtcattcacgtgacttctccacagttc aaagccgggccagtcaagtttgaaaaggatgtttacagagcagaaataagtgaatttgct cctcccaacacacctgtggtcatggtaaaggccattcctgcttattcccatttgaggtat gtttttaaaagtacacctggaaaagctaaattcagtttaaattacaacactggtctcatt tctattttagaaccagttaaaagacagcaggcagcccattttgaacttgaagtaacaaca agtgacagaaaagcgtccaccaaggtcttggtgaaagtcttaggtgcaaatagcaatccc cctgaatttacccagacagcgtacaaagctgcttttgatgagaacgtgcccattggtact actgtcatgagcctgagtgccgtagaccctgatgagggtgagaacgggtacgtgacatac agtatcgcaaatttaaatcatgtgccgtttgcgattgaccatttcactggtgccgtgagt acgtcagaaaacctggactacgaactgatgcctcgggtttatactctgaggattcgtgca tcagactggggcttgccgtaccgccgggaagtcgaagtccttgctacaattactctcaat aacttgaatgacaacacacctttgtttgagaaaataaattgtgaagggacaattcccaga gatctaggcgtgggagagcaaataaccactgtttctgctattgatgcagatgaacttcag ttggtacagtatcagattgaagctggaaatgaactggatttctttagtttaaaccccaac tcgggggtattgtcattaaagcgatcgctaatggatggcttaggtgcaaaggtgtctttc cacagtctgagaatcacagctacagatggagaaaattttgccacaccattatatatcaac ataacagtggctgccagtcacaagctggtaaacttgcagtgtgaagagactggtgttgcc aaaatgctggcagagaagctcctgcaggcaaataaattacacaaccagggagaggtggag gatattttcttcgattctcactctgtcaatgctcacataccgcagtttagaagcactctt ccgactggtattcaggtaaaggaaaaccagcctgtgggttccagtgtaattttcatgaac tccactgaccttgacactggcttcaatggaaaactggtctatgctgtttctggaggaaat gaggatagttgcttcatgattgatatggaaacaggaatgctgaaaattttatctcctctt gaccgtgaaacaacagacaaatacaccctgaatattaccgtctatgaccttgggataccc cagaaggctgcgtggcgtcttctacatgtcgtggttgtcgatgccaatgataatccaccc gagtttttacaggagagctattttgtggaagtgagtgaagacaaggaggtacatagtgaa atcatccaggttgaagccacagataaagacctggggcccaacggacacgtgacgtactca attgttacagacacagacacattttcaattgacagcgtgacgggtgttgttaacatcgca cgccctctggatcgagagctgcagcatgagcactccttaaagattgaggccagggaccaa gccagagaagagcctcagctgttctccactgtcgttgtgaaagtatcactagaagatgtt aatgacaacccacctacatttattccacctaattatcgtgtgaaagtccgagaggatctt ccagaaggaaccgtcatcatgtggttagaagcccacgatcctgatttaggtcagtctggt caggtgagatacagccttctggaccacggagaaggaaacttcgatgtggataaactcagt ggagcagttaggatcgtccagcagttggactttgagaagaagcaagtgtataatctcact gtgagggccaaagacaagggaaagccagtttctctgtcttctacttgctatgttgaagtt gaggtggttgatgtgaatgagaacctgcacccacccgtgttttccagctttgtggaaaag gggacagtgaaagaagatgcacctgttggttcattggtaatgacggtgtcggctcatgat gaggacgccagaagagatggggagatccgatactccattagagatggctctggcgttggt gttttcaaaataggtgaagagacaggtgtcatagagacgtcagatcgactggaccgtgaa tcgacctcccattattggctaacagtctttgcaaccgatcagggtgtcgtgcctctttca tcgttcatagagatctacatagaggttgaggatgtcaatgacaatgcaccacagacatca gagcctgtttattacccagaaatcatggaaaattctcctaaagatgtatctgtggtccag atcgaggcatttgatccagattcgagctctaatgacaagctcatgtacaaaattacaagt ggaaatccacaaggattcttttcaatacatcctaaaacaggtctcatcacaactacgtca aggaagctagaccgagaacagcaagatgaacacatattagaggttactgtgacagacaat ggtagtccccccaaatcaaccattgcaagagtcattgtgaaaatccttgatgaaaatgac aacaaacctcagtttctgcaaaagttctacaaaatcagactccctgagcgggaaaagcca gaccgagaaagaaatgccagacgggagccgctctatcacgtcatagccaccgacaaggat gagggccccaatgcagaaatctcctacagcatcgaagacgggaatgagcatggcaaattt ttcatcgaaccgaaaactggagtggtttcgtccaagaggttttcagcagctggagaatat gatattctttcaattaaggcagttgacaatggtcgccctcaaaagtcatcaaccaccaga ctccatattgaatggatctccaagcccaaaccgtccctggagcccatttcatttgaagaa tcattttttacctttactgtgatggaaagtgaccccgttgctcacatgattggagtaata tctgtggagcctcctggcatacccctttggtttgacatcactggtggcaactacgacagt cacttcgatgtggacaagggaactggaaccatcattgttgccaaacctcttgatgcagaa cagaagtcaaactacaacctcacagtcgaggctacagatggaaccaccactatcctcact caggtattcatcaaagtaatagacacaaatgaccatcgtcctcagttttctacatcaaag tatgaagttgttattcctgaagatacagcgccagaaacagaaattttgcaaatcagtgct gtggatcaggatgagaaaaacaaactaatctacactctgcagagcagtagagatccactg agtctcaagaaatttcgtcttgatcctgcaaccggctctctctatacttctgagaaactg gatcatgaagctgttcaccagcacaccctcacggtcatggtacgagatcaagatgtgcct gtaaaacgcaactttgcaaggattgtggtcaatgtcagcgacacgaatgaccacgccccg tggttcaccgcttcctcctacaaagggcgggtttatgaatcggcagccgttggctcagtt gtgttgcaggtgacggctctggacaaggacaaagggaaaaatgctgaagtgctgtactcg atcgagtcaggaaatattggaaattcttttatgattgatcctgtcttgggctctattaaa actgccaaagaattagatcgaagtaaccaagcggagtatgatttaatggtaaaagctaca gataagggcagtccaccaatgagtgaaataacttctgtgcgtatctttgtcacaattgct gacaacgcctctccgaagtttacatcaaaagaatattctgttgaacttagtgaaactgtc agcattgggagtttcgttgggatggttacagcccatagtcaatcatcagtggtgtatgaa ataaaagatggaaatacaggtgatgcttttgatattaatccacattctggaactatcatc actcagaaagccctggactttgaaactttgcccatttacacattgataatacaaggaact aacatggctggtttgtccactaatacaacggttctagttcacttgcaggatgagaatgac aacgcgccagtttttatgcaggcagaatatacaggactcattagtgaatcagcctcaatt aacagcgtggtcctaacagacaggaatgtcccactggtgattcgagcagctgatgctgat aaagactcaaatgctttgcttgtatatcacattgttgaaccatctgtacacacatatttt gctattgattctagcactggtgctattcatacagtactaagtctggactatgaagaaaca agtatttttcactttaccgtccaagtgcatgacatgggaaccccacgtttatttgctgag tatgcagcgaatgtaacagtacatgtaattgacattaatgactgcccccctgtgtttgcc aagccattatatgaagcatctcttttgttaccaacatacaaaggagtaaaagtcatcaca gtaaatgctacagatgctgattcaagtgcattctcacagttgatttactccatcaccgaa ggcaacatcggggagaagttttctatggactacaagactggtgctctcactgtccaaaac acaactcagttaagaagccgctacgagctaaccgttagagcttccgatggcagatttgcc ggccttacctctgtcaaaattaatgtgaaagaaagcaaagaaagtcacctaaagtttacc caggatgtctactctgcggtagtgaaagagaattccaccgaggccgaaacattagctgtc attactgctattgggaatccaatcaatgagcctttgttttatcacatcctcaacccagat cgcagatttaaaataagccgcacttcaggagttctgtcaaccactggcacgcccttcgat cgtgagcagcaggaggcgtttgatgtggttgtagaagtgacagaggaacataagccttct gcagtggcccacgttgtcgtgaaggtcattgtagaagaccaaaatgataatgcgccggtg tttgtcaaccttccctactacgccgttgttaaagtggacactgaggtgggccatgtcatt cgctatgtcactgctgtagacagagacagtggcagaaacggggaagtgcattactacctc aaggaacatcatgaacactttcaaattggacccttgggtgaaatttcactgaaaaagcaa tttgagcttgacaccttaaataaagaatatcttgttacagtggttgcaaaagatggaggg aacccggccttttcagcggaagttatcgttccgatcactgtcatgaataaagccatgcct gtgtttgaaaaacctttctacagtgcagagattgcagagagcatccaggtgcacagccct gtggtccacgtgcaggctaacagcccggaaggcctgaaagtgttctacagcatcacagac ggagaccctttcagccagttcactattaacttcaatactggagttatcaatgtcatagct cctctggactttgaggcccacccggcatataagctgagcatacgcgcaactgactccttg acgggcgctcatgctgaagtatttgtggacatcatagtagacgacatcaatgataaccct cctgtgtttgctcagcagtcttatgcggtgaccctgtctgaggcatctgtaattggaacg tctgttgttcaagttagagccaccgattctgattcagaaccaaatagaggaatctcatac cagatgtttgggaatcacagcaagagtcatgatcattttcatgtagacagcagcactggc ctcatctcactactcagaaccctggattacgagcagtcccggcagcacacgatttttgtg agggcagttgatggtggtatgcccacgctgagcagtgatgtgattgtcacggtggacgtt accgacctcaatgataatccaccactctttgaacaacagatttatgaagccagaattagc gagcacgcccctcatgggcatttcgtgacctgtgtaaaagcctatgatgcagacagttca gacatagacaagttgcagtattccattctgtctggcaatgatcataaacattttgtcatt gacagtgcaacagggattatcaccctctcaaacctgcaccggcacgccctgaagccattt tacagtcttaacctgtcagtgtctgatggagtttttagaagttccacccaggttcatgta actgtaattggaggcaatttgcacagtcctgctttccttcagaacgaatatgaagtggaa ctagctgaaaacgctcccctacataccctggtgatggaggtgaaaactacggatggggat tctggtatttatggtcacgttacttaccatattgtaaatgactttgccaaagacagattt tacataaatgagagaggacagatatttactttggaaaaacttgatcgagaaaccccggcg gagaaagtgatctcagtccgtttaatggctaaggatgctggaggaaaagttgctttctgc accgtgaatgtcatccttacagatgacaatgacaatgcaccacaatttcgagcaaccaaa tacgaagtgaatatcgggtccagtgctgctaaagggacttcagtcgttaaagttcttgca agtgatgccgatgagggctccaatgccgacatcacctatgccattgaagcagactctgaa agtgtaaaagagaatttggaaattaacaaactgtccggcgtaatcactacaaaggagagc ctcattggcttggaaaatgaattcttcactttctttgttagagctgtggataatgggtct ccatcaaaagaatctgttgttcttgtctatgttaaaatccttccaccggaaatgcagctt ccaaaattttcagaacctttctatacctttacagtgtcagaggacgtgcctattggaaca gagatagatctcatccgagcagaacatagtgggactgttctttacagcctggtcaaaggg aatactccagaaagcaatagggatgagtcctttgtgattgacagacagagcgggagactg aagttggagaagagtcttgatcatgagacaactaagtggtatcagttttccatactggcc aggtgcactcaagatgaccatgagatggtggcttctgtagatgttagtatccaagtgaaa gatgcaaatgacaacagcccggtctttgaatctagtccatatgaggcattcattgttgaa aacctgccagggggaagtagagtaattcagatcagggcatctgatgctgactcaggaacc aacggccaagttatgtatagcctggatcagtcacaaagtgtggaagtcattgaatccttt gccattaacatggaaacaggctggattacaactttaaaggaacttgaccatgaaaagaga gacaattaccagattaaagtggttgcatcagatcatggtgaaaagatccagctatcctcc acagccattgtggatgttaccgtcaccgatgtcaacgatagtccaccacgattcacggcc gagatctataaagggactgtgagtgaggatgacccccaaggtggggtgattgccatctta agtaccacggatgctgattctgaagagatcaacagacaagttacatatttcataacagga ggggatcctttaggacagtttgccgttgaaactatacagaatgaatggaaggtatatgtg aagaaacctctagacagggaaaaaagggacaattaccttcttactatcacggcaactgat ggcaccttctcatcaaaagcgatagttgaagtgaaagttctggatgcaaatgacaacagt ccagtttgtgaaaagactttatattcagacactattcctgaagacgtccttcctggaaaa ttgatcatgcagatctctgctacagacgcagacatccgctctaacgctgaaattacttac acgttattgggttcaggtgcagaaaaattcaaactaaatccagacacaggtgaactgaaa acgtcaaccccccttgatcgtgaggagcaagctgtttatcatcttctcgtcagggccaca gatggaggaggaagattctgccaagccagtattgtgctcacgctagaagatgtgaacgat aacgcccccgaattctctgccgatccttatgccatcaccgtgtttgaaaacacagagccg ggaacgctgctgacaagagtgcaggccacagatgccgacgcaggattaaatcggaagatt ttatactcactgattgactctgctgatgggcagttctccattaacgaattatctggaatt attcagttagaaaaacctttggacagagaactccaggcagtatacaccctctctttgaaa gctgtggatcaaggcttgccaaggaggctgactgccactggcactgtgattgtatcagtt cttgacataaatgacaacccccctgtgtttgagtaccgtgaatatggtgccaccgtgtct gaggacattcttgttggaactgaagttcttcaagtgtatgcagcaagtcgggatattgaa gcaaatgcagaaatcacctactcaataataagtggaaatgaacatgggaaattcagcata gattctaaaacaggggccgtatttatcattgagaatctggattatgagagctctcatgag tattacctaacagtagaggccactgatggaggcacgccttcactgagcgacgttgccact gtgaacgttaatgtaacagatatcaacgataatacccctgtgttcagccaagacacctac acgacagtcatcagtgaagatgccgttcttgagcagtctgtcatcacggttatggccgat gatgccgatggaccttccaacagccacatccactactcaattatagatggcaaccaagga agctcgttcacaattgaccccgtcaggggagaagtcaaagtgaccaaacttctcgaccga gaaacgatttcaggttacacgctcacggttcaagcttctgataatggcagtccacccaga gtcaacacgacgaccgtgaacatcgatgtgtccgatgtcaatgacaacgcgcccgtcttc tccaggggaaactacagtgtcattatccaggaaaataagccagtgggcttcagcgtgctg cagctggtagtaacagatgaggattcttcccataacggtccacccttcttctttactatt gtaactggaaatgatgagaaggcttttgaagttaacccgcaaggagtcctcctgacatca tctgccatcaagaggaaggagaaagatcattacttactgcaggtgaaggtggcagataat ggaaagcctcagttgtcatctttgacatacattgacattagggtaattgaggagagcatc tatccgcctgcgattttgcccctggagattttcatcacctcttctggagaagaatactca ggtggcgtcattgggaagatccatgccacagaccaggacgtgtatgatactctaacctac agtctcgaccctcagatggacaacctgttctctgtttccagcacagggggcaagctgata gcacacaaaaagctagacatagggcaataccttctcaatgtcagcgtaacagatgggaag ttcacgacggtggccgacatcacagtgcatatcagacaagtcacacaggagatgttgaac cacaccatcgcgatccgctttgccaacctcactccggaagaattcgttggtgactactgg cgcaacttccagcgagctttacggaacatcctgggtgtgaggaggaacgacatacagatt gttagtttgcagtcctctgaacctcacccacatctggacgtcttactttttgtagagaaa ccaggtagtgctcagatctcaacaaaacaacttctgcacaagattaactcttccgtgact gacattgaggaaatcattggagttaggatactgaatgtattccagaaactctgcgcggga ctggactgcccctggaagttctgcgatgaaaaggtgtctgtggatgaaagtgtgatgtca acacacagcacagccagactgagttttgtgactccccgccaccacagggcagcggtgtgt ctctgcaaagagggaaggtgcccacctgtccaccatggctgtgaagatgatccgtgccct gagggatccgaatgtgtgtctgatccctgggaggagaaacacacctgtgtctgtcccagc ggcaggtttggtcagtgcccagggagttcatctatgacactgactggaaacagctacgtg aaataccgtctgacggaaaatgaaaacaaattagagatgaaactgaccatgaggctcaga acatattccacgcatgcggttgtcatgtatgctcgaggaactgactatagcatcttggag attcatcatggaaggctgcagtacaagtttgactgtggaagtggccctggaattgtctct gttcagagcattcaggtcaatgatgggcagtggcacgcagtggccctggaagtgaatgga aactatgctcgcttggttctagaccaagttcatactgcatcgggcacagccccagggact ctgaaaaccctgaacctggataactatgtgttttttggtggccacatccgtcagcaggga acaaggcatggaagaagtcctcaagttggtaatggtttcaggggttgtatggactccatt tatttgaatgggcaggagctccctttaaacagcaaacccagaagctatgcacacatcgaa gagtcggtggatgtatctccaggctgcttcctgacggccacggaagactgcgccagcaac ccttgccagaatggaggcgtttgcaatccgtcacctgctggaggttattactgcaaatgc agtgccttgtacatagggacccactgtgagataagcgtcaatccgtgttcctccaagcca tgcctctatgggggcacgtgtgttgtcgacaacggaggctttgtttgccagtgtagagga ttatatactggtcagaggtgtcagcttagtccatactgcaaagatgaaccctgtaagaat ggcggaacatgctttgacagtttggatggcgccgtttgtcagtgtgattcgggttttagg ggagaaaggtgtcagagtgatatcgacgagtgctctggaaacccttgcctgcacggggcc ctctgtgagaacacgcacggctcctatcactgcaactgcagccacgagtacaggggacgt cactgcgaggatgctgcgcccaaccagtatgtgtccacgccgtggaacattgggttggcg gaaggaattggaatcgttgtgtttgttgcagggatatttttactggtggtggtgtttgtt ctctgccgtaagatgattagtcggaaaaagaagcatcaggctgaacctaaagacaagcac ctgggacccgctacggctttcttgcaaagaccgtattttgattccaagctaaataagaac atttactcagacataccaccccaggtgcctgtccggcctatttcctacaccccgagtatt ccaagtgactcaagaaacaatctggaccgaaattccttcgaaggatctgctatcccagag catcccgaattcagcacttttaaccccgagtctgtgcacgggcaccgaaaagcagtggcg gtctgcagcgtggcgccaaacctgcctcccccacccccttcaaactccccttctgacagc gactccatccagaagcctagctgggactttgactatgacacaaaagtggtggatcttgat ccctgtctttccaagaagcctctagaggaaaagccttcccagccatacagtgcccgggaa agcctgtctgaagtgcagtctctgagctccttccagtccgaatcgtgcgatgacaatggg tatcactgggatacatcagattggatgccaagcgttcctctgccggacatacaagagttc cccaactatgaggtgattgatgagcagacacccctgtactcagcagatccaaacgccatc gatacggactattaccctggaggctacgacatcgaaagtgattttcctccacccccagaa gacttccccgcagctgatgagctaccaccgttaccgcccgaattcagcaatcagtttgaa tccatccaccctcctagagacatgcctgccgcgggtagcttgggttcttcatcaagaaac cggcagaggttcaacttgaatcagtatttgcccaatttttatcccctcgatatgtctgaa cctcaaacaaaaggcactggtgagaatagtacttgtagagaaccccatgccccttacccg ccagggtatcaaagacacttcgaggcgcccgctgtcgagagcatgcccatgtctgtgtac gcctccaccgcctcctgctctgacgtgtcagcctgctgcgaagtggagtccgaggtcatg atgagtgactatgagagcggggacgacggccacttcgaagaggtgacgatcccgcccctg gattcccagcagcacacggaagtctga |
Protein Sequence |
>2195 : length: 4588 MGRHLALLLLLLLLFQHFGDSDGSQRLEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMG VYITHPAWEVRYKIVSGDSENLFKAEEYILGDFCFLRIRTKGGNTAILNREVKDHYTLIV KALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGT NGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSM AKLTVHIEQANECAPVITAVTLSPSELDRDPAYAIVTVDDCDQGANGDIASLSIVAGDLL QQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQF KAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYSHLRYVFKSTPGKAKFSLNYNTGLI SILEPVKRQQAAHFELEVTTSDRKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGT TVMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRA SDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQ LVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYIN ITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTL PTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPL DRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSE IIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQ AREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSG QVRYSLLDHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEV EVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVG VFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTS EPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTS RKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKP DRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEY DILSIKAVDNGRPQKSSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVI SVEPPGIPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILT QVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSRDPL SLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAP WFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIK TAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETV SIGSFVGMVTAHSQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGT NMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADAD KDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAE YAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITE GNIGEKFSMDYKTGALTVQNTTQLRSRYELTVRASDGRFAGLTSVKINVKESKESHLKFT QDVYSAVVKENSTEAETLAVITAIGNPINEPLFYHILNPDRRFKISRTSGVLSTTGTPFD REQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVI RYVTAVDRDSGRNGEVHYYLKEHHEHFQIGPLGEISLKKQFELDTLNKEYLVTVVAKDGG NPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEGLKVFYSITD GDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIVDDINDNP PVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTG LISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARIS EHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPF YSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGD SGIYGHVTYHIVNDFAKDRFYINERGQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFC TVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSE SVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQL PKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRL KLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVE NLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKR DNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAIL STTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATD GTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITY TLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQASIVLTLEDVND NAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQFSINELSGI IQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVS EDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHE YYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMAD DADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPR VNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTI VTGNDEKAFEVNPQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESI YPPAILPLEIFITSSGEEYSGGVIGKIHATDQDVYDTLTYSLDPQMDNLFSVSSTGGKLI AHKKLDIGQYLLNVSVTDGKFTTVADITVHIRQVTQEMLNHTIAIRFANLTPEEFVGDYW RNFQRALRNILGVRRNDIQIVSLQSSEPHPHLDVLLFVEKPGSAQISTKQLLHKINSSVT DIEEIIGVRILNVFQKLCAGLDCPWKFCDEKVSVDESVMSTHSTARLSFVTPRHHRAAVC LCKEGRCPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSYV KYRLTENENKLEMKLTMRLRTYSTHAVVMYARGTDYSILEIHHGRLQYKFDCGSGPGIVS VQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKTLNLDNYVFFGGHIRQQG TRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCFLTATEDCASN PCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVDNGGFVCQCRG LYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGA LCENTHGSYHCNCSHEYRGRHCEDAAPNQYVSTPWNIGLAEGIGIVVFVAGIFLLVVVFV LCRKMISRKKKHQAEPKDKHLGPATAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSI PSDSRNNLDRNSFEGSAIPEHPEFSTFNPESVHGHRKAVAVCSVAPNLPPPPPSNSPSDS DSIQKPSWDFDYDTKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNG YHWDTSDWMPSVPLPDIQEFPNYEVIDEQTPLYSADPNAIDTDYYPGGYDIESDFPPPPE DFPAADELPPLPPEFSNQFESIHPPRDMPAAGSLGSSSRNRQRFNLNQYLPNFYPLDMSE PQTKGTGENSTCREPHAPYPPGYQRHFEAPAVESMPMSVYASTASCSDVSACCEVESEVM MSDYESGDDGHFEEVTIPPLDSQQHTEV |